宫腔镜联合激素治疗子宫非典型性息肉样腺肌瘤的疗效分析  

Analysis of curative effect of hysteroscopic combined hormone therapy on atypical polypoid adenomyoma of uterus

作　　者：尹玲玲 王纪云 Yin Lingling;Wang Jiyun(Department of Gynaecology,Center Hospital of Rizhao,Rizhao Shandong,276800,China)

机构地区：[1]日照市中心医院妇科,山东日照276800

出　　处：《中外女性健康研究》2024年第8期8-10,78,共4页Women＇s Health Research

摘　　要：目的:观察宫腔镜联合激素治疗非典型息肉样腺肌瘤的疗效,初步研讨宫腔镜联合激素治疗非典型息肉样腺肌瘤的价值。方法:收集2020年3月至2023年2月在本院明确诊断为非典型息肉样腺肌瘤的患者资料,选取82例符合纳入标准的非典型息肉样腺肌瘤患者,根据治疗方案分为对照组41例(宫腔镜治疗)、观察组41例(宫腔镜联合激素治疗),对比两组的月经失血评分、子宫内膜厚度、血管内皮生长因子水平(VEGF)、血清促黄体生成素(LH)、卵泡刺激素(FSH)、并发症发生情况以及治疗12个月后妊娠和复发情况。结果:治疗前,两组月经失血评分、子宫内膜厚度、VEGF、LH、FSH比较,无统计学差异(P>0.05);治疗后,观察组月经失血评分(53.68±6.12)分和子宫内膜厚度(6.15±1.05)mm、血清LH(38.36±4.42)U/L、FSH(30.51±3.02)U/L、VEGF(70.56±9.76)ng/L、并发症发生率(2.44%)和复发率(4.88%)均低于对照组,妊娠成功率(39.02%)高于对照组,差异有统计学意义(P<0.05)。结论:宫腔镜联合激素治疗非典型息肉样腺肌瘤能显著减少子宫异常失血,改善子宫内膜厚度、激素水平和血管内皮生长因子水平,降低复发风险,提高妊娠成功率。Objective:To observe the efficacy of hysteroscopy combined with hormone in the treatment of atypical polypoid adenomyoma,and to study the value of hysteroscopy combined with hormone in the treatment of atypical polypoid adenomyoma.Methods:The data of patients with atypical polypoid adenomyoma diagnosed in our hospital from March 2020 to February 2023 were collected,and 82 patients with atypical polypoid adenomyoma who met the inclusion criteria were selected,according to the treatment plan,they were divided into control group(41 cases)(hysteroscopy)and observation group(41 cases)(hysteroscopy combined with hormone therapy).The menstrual blood loss score,endometrial thickness,vascular endothelial growth factor(VEGF),Serum Luteinizing hormone(LH),follicle stimulating hormone(FSH),complications,and pregnancy and recurrence after 12 months of treatment.Results:Before treatment,two groups of menstrual blood loss score,endometrial thickness,VEGF,LH,FSH comparison,no statistical difference(P>0.05);After treatment,in the observation group,menstrual blood loss score(53.68±6.12),endometrial thickness(6.15±1.05)mm,serum LH(38.36±4.42)U/L,FSH(30.51±3.02)U/L,VEGF(70.56±9.76)ng/L,complication rate(2.44%)and recurrence rate(4.88%)were significantly lower than the control group,the pregnancy success rate(39.02%)was significantly higher than the control group,the difference was statistically significant(P<0.05).Conclusion:Hysteroscopy combined with hormone in the treatment of atypical polypoid adenomyoma can significantly reduce abnormal uterine blood loss,improve endometrial thickness,hormone levels and vascular endothelial growth factor levels,reduce the risk of recurrence,and improve the success rate of pregnancy,worth promoting.

关 键 词：宫腔镜 激素 子宫非典型性息肉样腺肌瘤 性激素 

分 类 号：R737.33[医药卫生—肿瘤]