腹腔镜辅助下直肠外翻拖出式手术治疗直肠癌的临床疗效及并发症发生情况研究  

Study on the clinical effect and complications of laparoscope-assisted rectal valgus and drag out surgery for rectal cancer

作　　者：梁泉江 Liang Quanjiang(The Guangxi Zhuang Autonomous Region Brain Hospital,Liuzhou,Guangxi 545005,China)

机构地区：[1]广西壮族自治区脑科医院,广西柳州545005

出　　处：《首都食品与医药》2024年第16期29-31,共3页Capital Food Medicine

摘　　要：目的研究腹腔镜辅助下直肠外翻拖出式手术治疗直肠癌的效果.方法回顾性选取2020年2月-2023年2月广西壮族自治区脑科医院直肠癌患者50例,依据手术方法分为腹腔镜辅助下直肠前切除手术组(直肠前切除手术组)、腹腔镜辅助下直肠外翻拖出式手术组(外翻拖出式手术组)两组,每组各25例.统计分析两组围术期指标、肛肠动力学指标、氧化应激指标、炎性因子水平、免疫功能、术后并发症发生情况、肿瘤转移、复发情况.结果外翻拖出式手术组患者的术中出血量少于直肠前切除手术组(P<0.05),手术时间、肠功能恢复时间、住院时间均短于直肠前切除手术组(P<0.05),术后2周、6个月排便次数均少于直肠前切除手术组(P<0.05).外翻拖出式手术组患者的SAA、CRP、AIRT、MDA、IL-6、IL-8、MMP-9、TNF-α、VEGF、CD8^(+)水平均低于直肠前切除手术组(P<0.05),MSP、ARP、RRP、MTV、HPZ、SOD、CD4^(+)、CD4^(+)/CD8^(+)水平均高于直肠前切除手术组(P<0.05).外翻拖出式手术组患者的术后并发症发生率、肿瘤转移率均低于直肠前切除手术组(P<0.05).结论腹腔镜辅助下直肠外翻拖出式手术治疗直肠癌较直肠前切除手术的临床效果好,并发症发生率更低.Objective To study the effect of laparoscope-assisted rectal valgus and drag out surgery in the treatment of rectal cancer.Methods 50 cases of rectal cancer patients in our hospital from February 2020 to February 2023 were retrospectively selected,and were divided into two groups according to surgical methods:laparoscopic-assisted proctorectal resection operation group(prerectal resection operation group)and laparoscopic-assisted proctorectal valgus and valgus drag out operation group(valgus drag out operation group),with 25 cases each.Perioperative indexes,anorectal dynamics indexes,oxidative stress indexes,inflammatory factor levels,immune function,postoperative complications,tumor metastasis and recurrence of the two groups were statistically analyzed.Results The amount of intraoperative blood loss in the varsion and drag operation group was less than that in the prerectal resection group(P<0.05),the operation time,intestinal function recovery time and hospital stay were shorter than that in the prerectal resection group(P<0.05),and the frequency of defecation 2 weeks and 6 months after the operation was less than that in the prerectal resection group(P<0.05).The levels of SAA,CRP,AIRT,MDA,IL-6,IL-8,MMP-9,TNF-α,VEGF and CD8^(+)in the varsion and drag operation group were lower than those in the prerectal resection group(P<0.05).The levels of MSP,ARP,RRP,MTV,HPZ,SOD,CD4^(+),CD4^(+)/CD8^(+)were all higher than those in prerectal resection group(P<0.05).The incidence of postoperative complications and the rate of tumor metastasis in the valgus and drag operation group were lower than those in the prerectal resection group(P<0.05).Conclusion Compared with prerectal resection,laparoscope-assisted rectal valvaration and drag out surgery has better clinical effect and lower complication rate.

关 键 词：直肠癌 腹腔镜辅助下 直肠外翻脱出式手术 并发症 肿瘤转移 复发 

分 类 号：R735.37[医药卫生—肿瘤]