声动力疗法在泌尿系肿瘤中的研究进展  

Research progress of sonodynamic therapy in urological tumors

作　　者：沈琦 霍梦萍 张杨 盖永浩 Shen Qi;Huo Mengping;Zhang Yang;Gai Yonghao(Department of Ultrasound Medicine,Shandong Provincial Hospital Affiliated to Shandong First Medical University,Jinan 250021,China)

机构地区：[1]山东第一医科大学附属省立医院超声医学科,济南250021

出　　处：《中华泌尿外科杂志》2024年第7期563-566,共4页Chinese Journal of Urology

基　　金：国家自然科学基金(82102040);山东省泰山学者项目(tsqnz20221171)。

摘　　要：声动力疗法(SDT)通过低强度超声与声敏剂结合,提供了一种非侵人性靶向杀伤肿瘤细胞的治疗策略。与其他部位的肿瘤相比,泌尿系统肿瘤具有良好的治疗声窗,结合低频超声特殊的强穿透性、高靶向性等优势,SDT在泌尿系肿瘤中具有较高的治疗效率和广阔应用前景。Sonodynamic therapy(SDT)provides a non-invasive therapeutic strategy for killing tumor cells by using low-intensity ultrasound combined with sonosensitizer.Compared with other tumors,urinary system tumors have a good sound window for treatment.Combined with the advantages of lowfrequency ultrasound,such as strong penetration and high targeting,SDT has efficient treatment efficiency and broad application prospects in urological tumors.

关 键 词：声动力疗法 纳米粒子 多模态疗法 泌尿系肿瘤 

分 类 号：R737.1[医药卫生—肿瘤]