纤维蛋白原样蛋白1在肝细胞癌中的研究进展  

Research progress of fibrinogen-like protein 1 in hepatocellular carcinoma

作　　者：宁源佳 韦花媚 NING Yuanjia;WEI Huamei(Graduate School of Youjiang Medical University for Nationalities,Baise 533000;Pathology Department,Affiliated Hospital of Youjiang Medical University for Nationalities,Baise 533000,China)

机构地区：[1]右江民族医学院研究生学院,广西百色533000 [2]右江民族医学院附属医院病理科,广西百色533000

出　　处：《临床医学研究与实践》2024年第24期187-190,共4页Clinical Research and Practice

基　　金：2022年度国家自然科学基金-地区科学基金项目(No.82260593)。

摘　　要：纤维蛋白原样蛋白1(FGL1)是纤维蛋白原家族中的一员,现阶段许多研究表明FGL1与肝细胞癌(HCC)的发生密切相关,其有望成为HCC新的免疫治疗靶点。然而对FGL1的研究成果还不能完全揭示其在HCC发生发展过程中的作用。本文综述了FGL1在HCC中的研究进展,以期为FGL1与HCC相关性的详细机制进一步解析。Fibrinogen-like protein 1(FGL1)is a member of the fibrinogen family,at present,many studies have shown that FGL1 is closely related to the occurrence of hepatocellular carcinoma(HCC),and it is expected to become a new immunotherapy target for HCC.However,the research results of FGL1 have not fully reveal its role in the occurrence and development of HCC.This paper reviews the research progress of FGL1 in HCC,in order to further analyze the detailed mechanism of the correlation between FGL1 and HCC.

关 键 词：纤维蛋白原样蛋白1 淋巴细胞活化基因3 肝细胞癌 

分 类 号：R735.7[医药卫生—肿瘤]