从《伤科大成》分析清代医家赵濂治疗骨伤科疾病的组方规律及思想  

Analysis of Qing Dynasty Medical ZHAO Lian's Prescription Rule and Thought of Treating Orthopedics and Traumatology Diseases based on“Shangke Dacheng”

作　　者：戴亚南 陈斌[2] DAI Yanan;CHEN Bin(The First Clinical Medical College of Anhui University of Chinese Medicine,Anhui Hefei 230031,China;The First Affiliated Hospital of Anhui University of Chinese Medicine,Anhui Hefei 230031,China)

机构地区：[1]安徽中医药大学第一临床医学院,安徽合肥230031 [2]安徽中医药大学第一附属医院,安徽合肥230031

出　　处：《中医药临床杂志》2024年第8期1513-1518,共6页Clinical Journal of Traditional Chinese Medicine

摘　　要：目的:基于数据挖掘对清代骨伤科著作《伤科大成》治疗骨伤科疾病的组方用药规律进行探究,希望对临床用药提供新思路。方法:整理《伤科大成》治疗骨伤科疾病方剂共41首,利用Microsoft Excel 2016、IBM SPSS Modeler18.0、IBM SPSS Statistics 26.0进行关联分析和聚类分析。结果:共计纳入41首医案处方,涉及139种中药,用药总频次为470次,高频药物(>10次)共7味,最高频次药物为当归,其次为乳香、红花、没药、白芍、川芎、枳壳、陈皮、地黄、三七、熟地黄、苏木等,药物药味以苦、辛、甘为主,药性以寒、温为主,归经以肝、心、脾、肺经为主,关联分析共得到核心药物7组,聚类分析将20味中药分为4类。结论:赵濂治疗骨伤科疾病以清热凉血、行气止痛、活血化瘀、补益肝肾为主,可为中医骨伤科临床提供参考。Objective:To explore the prescription and medication rules of the Qing Dynasty orthopedic book“Shangke Dacheng”for the treatment of orthopedic diseases based on data mining,hoping to provide new ideas for clinical medi-cation.Methods:A total of 41 prescriptions for the treatment of orthopedic diseases in“Shangke Dacheng”were sorted out,and association analysis and cluster analysis were performed using Microsoft Excel 2016,IBM SPSS Modeler18.0,and IBM SPSS Statistics 26.0.Results:A total of 41 medical case prescriptions were included,involving 139 kinds of Chinese medicines,with a total frequency of 470 times.There were 7 high-frequency drugs(>10 times),with the high-est frequency being angelica,followed by frankincense,safflower,myrrh,white peony,Chuanxiong,Fructus Aurantii,Tangerine Peel,Rehmannia,Notoginseng,Cooked Rehmannia,And Sappan Wood.The taste of the drugs was mainly bitter,pungent,and sweet,the properties were mainly cold and warm,and the meridians were mainly liver,heart,spleen,and lung.The association analysis obtained a total of 7 core drug groups,and the cluster analysis divided the 20 Chinese medicines into 4 categories.Conclusion:ZHAO Lian’s treatment of orthopedic diseases mainly focused on clearing heat and cooling blood,promoting Qi and relieving pain,promoting blood circulation and removing blood stasis,and tonifying the liver and kidney,which can provide a reference for the clinical practice of orthopedics in tradi-tional Chinese medicine.

关 键 词：《伤科大成》 赵濂 数据挖掘 骨伤科 

分 类 号：R223.1[医药卫生—中医基础理论]