Changes on Stroke Burden Attributable to Ambient Fine Particulate Matter in China  

作　　者：Jingyu Wang Yan Wang Xiaohua Liang Keyong Huang Fangchao Liu Shufeng Chen Xiangfeng Lu Jianxin Li 

机构地区：[1]Department of Epidemiology,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100037,China [2]Key Laboratory of Cardiovascular Epidemiology,Chinese Academy of Medical Sciences,Beijing 100037,China [3]Department of Clinical Epidemiology and Biostatistics,Children’s Hospital of Chongqing Medical University,National Clinical Research Center for Child Health and Disorders,Ministry of Education Key Laboratory of Child Development and Disorders,Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory Disease,Chongqing 400016,China

出　　处：《Biomedical and Environmental Sciences》2024年第8期823-833,共11页生物医学与环境科学（英文版）

基　　金：supported by National Key Research and Development Program of China(2018YFE0115300,2022YFC3600800,2017YFC0211706);Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences(2021-I2M-1-010);National Natural Science Foundation of China(82073658,82070473);National High Level Hospital Clinical Research Funding(2022-GSP-GG-1,2022-GSP-GG-2);Research Unit of Prospective Cohort of Cardiovascular Diseases and Cancers,CAMS(2019RU038);National Clinical Research Center for Cardiovascular Diseases,Fuwai Hospital,CAMS(NCRC2020006)。

摘　　要：Objective In recent decades,China has implemented a series of policies to address air pollution.We aimed to assess the health effects of these policies on stroke burden attributable to ambient fine particulate matter(PM_(2.5)).Methods Joinpoint regression was applied to explore the temporal tendency of stroke burden based on data from the Global Burden of Disease 2019 study.Results The age-standardized rates of disability-adjusted life year(DALY)for stroke attributable to ambient PM2.5 in China,increased dramatically during 1990-2012,subsequently decreased at an annual percentage change(APC)of-1.98[95% confidence interval(CI):-2.26,-1.71]during 2012-2019.For ischemic stroke(IS),the age-standardized DALY rates doubled from 1990 to 2014,and decreased at an APC of-0.83(95%CI:-1.33,-0.33)during 2014-2019.Intracerebral hemorrhage(ICH)showed a substantial increase in age-standardized DALY rates from 1990 to 2003,followed by declining trends,with APCs of-1.46(95%CI:-2.74,-0.16)during 2003-2007 and-3.33(95%CI:-3.61,-3.06)during 2011-2019,respectively.Conversely,the age-standardized DALY rates for subarachnoid hemorrhage(SAH)generally declined during 1990-2019.Conclusion Our results clarified the dynamic changes of the ambient PM_(2.5)-attributable stroke burden in China during 1990-2019,highlighting the health effects of air quality improvement policies.

关 键 词：Ambient fine particulate matter STROKE Disease burden Temporal trend POLICY 

分 类 号：X513[环境科学与工程—环境工程] R743.3[医药卫生—神经病学与精神病学]