Effects of Curcumin on Neuroinflammation and the Nrf2/HO-1 Pathway in Rat Brains Following Gas Explosion  

作　　者：Xinwen Dong Yaguang Su Zheng Luo Lyufei Deng Xiaofeng Han Yifang Liang Sanqiao Yao Weidong Wu Jia Cao Linqiang Tian Yichun Bai Wenjie Ren 

机构地区：[1]Health School of Public Health,Xinxiang Medical University,Xinxiang 453003,Henan,China [2]Toxicology Research Institute,PLA Army Medical University,Chongqing 400038,China [3]Institute of Trauma and Orthopaedics,Xinxiang Medical University,Xinxiang 453003,Henan,China [4]Institutes of Health Central Plains,Xinxiang Medical University,Xinxiang 453003,Henan,China

出　　处：《Biomedical and Environmental Sciences》2024年第8期943-947,共5页生物医学与环境科学（英文版）

基　　金：supported by the National Natural Science Foundation of China[U2004102];the Science and Technology Project of Henan Province[232102311071];the Natural Science Foundation of Henan Province[202300410312]。

摘　　要：Gas explosions,a major occupational hazard in China’s coal industry,endanger the lives and health of miners.These explosions cause a specific type of traumatic brain injury with complex mechanisms,leading to disability and death.A study by Zhao et al.using magnetic resonance imaging on 49 gas explosion survivors revealed significant damage to brain regions like the hippocampus and cerebral cortex.

关 键 词：damage NRF2 CEREBRAL 

分 类 号：R285.5[医药卫生—中药学]