骨髓增生异常综合征/肿瘤和急性髓系白血病WHO分类和国际共识分类比较  

Comparison the WHO classification and the International Consensus Classification for myelodysplastic syndromes/neoplasms and acute myeloid leukemia

作　　者：刘义刚 曲惠廷 李丽 王晶 房孝生 王倩 王子娥 孙慧 黄敏 张健 张之芬 甄晓玲 赵文博 武焕玲 Liu Yigang;Qu Huiting;Li Li;Wang Jing;Fang Xiaosheng;Wang Qian;Wang Zie;Sun Hui;Huang Min;Zhang Jian;Zhang Zhifen;Zhen Xiaoling;Zhao Wenbo;Wu Huanling(Department of Clinical Laboratory Medicine,Shandong Provincial Hospital Affiliated to Shandong First Medical University,Jinan 250021,China;Department of Hematology Medicine,Shandong Provincial Hospital Affiliated to Shandong First Medical University,Jinan 250021,China;Department of Clinical Laboratory,Qingdao Central Hospital,Qingdao 266000,China)

机构地区：[1]山东第一医科大学附属省立医院临床医学检验部,济南250021 [2]山东第一医科大学附属省立医院血液内科,济南250021 [3]青岛市立医院检验科,青岛266000

出　　处：《中华检验医学杂志》2024年第8期844-851,共8页Chinese Journal of Laboratory Medicine

基　　金：山东第一医科大学附属省立医院横向科研项目(HXKT0010)。

摘　　要：世界卫生组织(WHO)有关造血与淋巴组织肿瘤的国际诊断和分类标准(WHO-HEAM)自2001年以来,经历了多个版本的升级和修订,对先前一些肿瘤的诊断和分类标准进行了更新、澄清和细化,同时增加了许多新的遗传学和分子生物学亚型。由于大量临床和科学研究结果的出现以及专家对诊断分类的分歧,2022年出现了两个分类建议,即2022年Leukemia杂志上发布的第5版WHO造血与淋巴组织分类(WHO-HAEM5)和Blood杂志上发表的国际共识分类(ICC)。这两个方案对造血与淋巴组织肿瘤的分类有所不同,给临床实验室诊断和治疗带来了一些困扰和挑战。The World Health Organization(WHO)classification serves as the internationally recognized standard for diagnosing and classifying hematopoietic and lymphoid tissue tumors(WHO-HEAM).Since 2001,it has undergone multiple upgrades and revisions,updating,clarifying,and refining previous tumor diagnostic and classification standards while incorporating numerous new genetic and molecular biological subtypes.In 2022,two classification proposals emerged due to a wealth of clinical and scientific research results:the fifth edition of the WHO hematopoietic and lymphoid tissue classification(WHO-HAEM5),published in Leukemia journal;and the International Consensus Classification(ICC),published in Blood journal.These two schemes differ in their approach to classifying hematopoietic and lymphoid tissue tumors,posing challenges for clinical laboratory diagnosis and treatment.

关 键 词：血液肿瘤 白血病 WHO造血与淋巴组织肿瘤分类 国际共识分类 骨髓增生异常综合征/肿瘤 急性髓系白血病 

分 类 号：R733.3[医药卫生—肿瘤] R733.71[医药卫生—临床医学]