基于TOUS的儿童癌症相关认知障碍影响因素的研究进展  

Research progress in influencing factors of cancer-related cognitive impairment in children based on theory of unpleasant symptoms

作　　者：陈泽方 刘涛 莫霖[2] CHEN Zefang;LIU Tao;MO Lin(Department of Nursing,Affiliated Children’s Hospital of Chongqing Medical University/National Clinical Research Center for Child Health and Disorders/Ministry of Education Key Laboratory of Child Development and Disorders/Chongqing Key Laboratory of Pediatrics,Chongqing 400014,China;Department of Outpatients,Affiliated Children’s Hospital of Chongqing Medical University/National Clinical Research Center for Child Health and Disorders/Ministry of Education Key Laboratory of Child Development and Disorders/Chongqing Key Laboratory of Pediatrics,Chongqing 400014,China)

机构地区：[1]重庆医科大学附属儿童医院护理部/国家儿童健康与疾病临床医学研究中心/儿童发育疾病研究教育部重点实验室/儿科学重庆市重点实验室,重庆400014 [2]重庆医科大学附属儿童医院门诊部/国家儿童健康与疾病临床医学研究中心/儿童发育疾病研究教育部重点实验室/儿科学重庆市重点实验室,重庆400014

出　　处：《重庆医学》2024年第16期2536-2542,共7页Chongqing Medical Journal

基　　金：重庆市自然科学基金面上项目(CSTB2022NSCQ-MSX0082)。

摘　　要：不同类型肿瘤或常见的抗肿瘤治疗措施可导致患儿出现癌症相关认知障碍(CRCI)。依据不愉快症状理论(TOUS),该文总结了3个层面共计20个关键影响因素:生理层面包括疾病类型、治疗方式、治疗相关并发症、年龄、性别等;心理层面涵盖疲乏、焦虑、抑郁及睡眠障碍等;背景层面涉及家庭环境与社会经济地位、父母受教育程度及体育运动等,并对这些影响因素进行了阐述,旨在为该领域的进一步研究提供参考。Different types of tumors or common anti-tumor treatment measures can lead to cancer-related cognitive impairment(CRCI)appearance in pediatric patients.Based on the theory of unpleasant symptoms(TOUS),this paper summarizes a total of 20 key influencing factors in 3 levels:the physiological level includes the disease type,treatment method,treatment-related complications,age,gender,etc.;the psychological level encompasses fatigue,anxiety,depression,and sleep disturbances,etc.;the background level involves the family environment and socioeconomic status,parental education level,physical activity,etc.This paper elucidates these influencing factors to provide reference for further research in this field.

关 键 词：不愉快症状理论 儿童 癌症相关认知障碍 影响因素 综述 

分 类 号：R749.1[医药卫生—神经病学与精神病学]