微创环切术对牙列缺损种植患者炎症反应及牙槽嵴顶骨吸收的影响  

Effect of minimally invasive circumferential resection on inflammatory response and alveolar crest resorption in patients with dental defect implantation

作　　者：姚旭飞[1] 蓝博 季育[1] 周雪君 YAO Xu-fei;LAN Bo;JI Yu;ZHOU Xue-jun(Department of Stomatology,Lishui Hospital of Traditional Chinese Medicine,Lishui 323000,Zhejiang Province,China)

机构地区：[1]丽水市中医院口腔科,浙江丽水323000

出　　处：《上海口腔医学》2024年第4期398-402,共5页Shanghai Journal of Stomatology

基　　金：浙江省医药卫生科技计划项目(2020388455)。

摘　　要：目的:探讨微创环切术对牙列缺损种植患者炎症反应及牙槽嵴顶骨吸收的影响。方法:选择2021年6月—2023年6月在丽水市中医院接受牙列缺损种植术的患者198例,根据治疗方式分为微创组(n=100)和传统组(n=98)。微创组采用微创环切术,传统组采用传统翻瓣术。比较2组患者手术相关指标、炎症因子水平、疼痛介质、牙槽嵴顶骨吸收量、种植体松动情况、生活质量及并发症发生率。采用SPSS 27.0软件包对数据进行统计学分析。结果:微创组手术时间、术后VAS评分、术后疼痛反应时间均显著低于传统组(P<0.05)。微创组白细胞介素8(IL-8)、肿瘤坏死因子α(TNF-α)、干扰素γ(INF-γ)、血清淀粉样蛋白A(SAA)、P物质(SP)、降钙素基因相关肽(CGRP)、5羟色胺(5-HT)水平均显著低于传统组(P<0.05)。微创组患者牙槽嵴顶骨吸收量显著低于传统组(P<0.05),2组种植体松动度和种植体留存率相比无显著差异(P>0.05)。微创组患者OHIP-14量表各维度评分显著低于传统组(P<0.05)。微创组与传统组并发症发生率相比无显著差异(P<0.05)。结论:微创环切术相比传统翻瓣术,在减少手术时间、降低术后炎症因子和疼痛介质水平、减少牙槽嵴顶骨吸收量及提高口腔健康方面表现更优,可广泛用于牙列缺损种植术中。PURPOSE:To explore the impact of minimally invasive circumferential resection on inflammatory response and alveolar crest resorption in patients with dental defect implantation.METHODS:A total of 198 patients who received dental implantation in Lishui Hospital of Traditional Chinese Medicine from June 2021 to June 2023 were selected and divided into minimally invasive group(n=100)and traditional group(n=98)according to treatment methods.Minimally invasive surgery was performed in the minimally invasive group and traditional flap surgery was performed in the traditional group.Surgical related indicators,levels of inflammatory factors,pain mediators,alveolar crest bone resorption,implant loosening,quality of life and complication rates were compared between the two groups.SPSS 27.0 software package was used for statistical analysis.RESULTS:The surgery time,postoperative VAS scores and postoperative pain reaction time in the minimally invasive group were significantly lower than those in the traditional group(P<0.05).In the minimally invasive group,the concentrations of IL-8,TNF-α,INF-γ,serum amyloid A(SAA),substance P(SP),calcitonin gene-related peptide(CGRP)and 5-hydroxytryptamine(5-HT)were significantly lower than the traditional group(P<0.05).The amount of alveolar crest bone absorption in minimally invasive group was significantly lower than that in the traditional group(P<0.05).There was no significant differences in implant loosening and retention rates between the two groups(P>0.05).OHIP-14 scores across all dimensions in the minimally invasive group were significantly lower than in the traditional group(P<0.05).There was no significant difference in complication rate between the minimally invasive group and the traditional group(P<0.05).CONCLUSIONS:Compared with the traditional surgery,minimally invasive circumferential surgery has better performance in reducing operation time,postoperative inflammatory factors and pain mediators,alveolar crest and parietal bone absorption and improving oral health,which

关 键 词：牙列缺损 种植 微创环切术 炎症反应 牙槽嵴顶骨吸收 

分 类 号：R782.1[医药卫生—口腔医学]