梅花鹿头茬茸与再生茸酶解液免疫调节作用  

Immunomodulatory Effects of Enzymatic Solution from First-Cut and Regenerated Velvet Antler of Sika Deer

作　　者：李钇丹 李昌泽 张爱武 刘双文 鞠贵春 LI Yidan;LI Changze;ZHANG Aiwu;LIU Shuangwen;JU Guichun(College of Animal Science and Technology/College of Veterinary Medicine,Jilin Agricultural University,Changchun 130118,China;Mishan Animal Husbandry and Aquaculture Technology Service Center,Mishan 158300,China)

机构地区：[1]吉林农业大学动物科学技术学院/动物医学院,长春130118 [2]密山市畜牧水产技术服务中心,密山158300

出　　处：《经济动物学报》2024年第3期206-211,共6页Journal of Economic Animal

基　　金：吉林省科技发展计划项目(20200404012YY)。

摘　　要：为探究头茬茸与再生茸酶解液对小鼠免疫功能的影响,选取35只6周龄健康雄性小鼠,体重20~25 g,分为7组,对照组灌胃蒸馏水,6个试验组(头茬1组、头茬2组、头茬3组、再生1组、再生2组、再生3组)分别灌胃对应鹿茸所制酶解液,每只每日灌胃0.3 mL,连续灌胃14 d。试验结束后检测血清中免疫因子含量,计算肝脏指数、胸腺指数和脾脏指数。结果表明:试验组的脏器指数、免疫球蛋白A(IgA)、免疫球蛋白G(IgG)和免疫球蛋白M(IgM)的含量均显著高于对照组(P<0.05);头茬茸酶解液对脏器指数和免疫因子的调节作用高于再生茸。说明头茬茸组的免疫活性高于再生茸组。This study aims to investigate the effects of enzymatic lysis of first-cut velvet antler and regenerated velvet antler on immune function of mice.Thirty five 6 weeks old healthy male mice were selected with an average body weight of 20-25 g to divide into seven experimental groups.The control group was gavaged with distilled water.The other six experimental groups named first-cut velvet antler 1,first-cut velvet antler 2 and first-cut velvet antler 3 and regenerated 1,regenerated 2 and regenerated 3,were gavaged with the enzymatic solution prepared from different velvet antler.Each group was gavaged with 0.3 mL per day.The period of intragastric administration lasted 14 days.The blood of mouse eyeballs was taken to detect the content of immune factors in serum after the end of the trial cycle,and the liver index,thymus index and spleen index were calculated after dissection.The results showed that the visceral index and the expression level of immunoglobulin A(IgA),immunoglobulin G(IgG),and immunoglobulin M(IgM)were significantly higher in the experimental group than those in the control group(P<0.05).The visceral index and modulatory effects of immune factors was higher in the first-cut velvet antler group than those in the regenerated velvet antler group.The experiment proved that immune activity was higher in the firstcut antler group than that in the regenerated velvet antler group.

关 键 词：梅花鹿 头茬茸 再生茸 酶解 小鼠 免疫调节 

分 类 号：S825[农业科学—畜牧学]