血塞通联合生长抑素治疗急性胰腺炎的临床疗效研究  

Clinical Efficacy of Xuesaitong Combined with Somatostatin in the Treat⁃ment of Acute Pancreatitis

作　　者：刘俊 邢朝富 张德平 LIU Jun;XING Chaofu;ZHANG Deping(Department of Gastroenterology,Dantu District People′s Hospital of Zhenjiang,Zhenjiang 212000,Jiangsu,China)

机构地区：[1]镇江丹徒区人民医院消化内科,江苏镇江212000

出　　处：《系统医学》2024年第13期104-108,共5页Systems Medicine

摘　　要：目的探究血塞通联合生长抑素治疗急性胰腺炎的临床疗效。方法非随机选取2021年1月—2023年6月江苏镇江丹徒区人民医院收治的60例急性胰腺炎患者为研究对象,按照不同治疗方法分为对照组(予以生长抑素治疗)、观察组(予以血塞通、生长抑素联合治疗),每组30例,对比两组的临床疗效、炎性因子水平、血淀粉酶及尿淀粉酶、病情恢复情况。结果观察组的临床总有效率为93.33%,高于对照组的73.33%,差异有统计学意义(χ^(2)=4.320,P<0.05)。观察组血清炎性因子水平、血淀粉酶、尿淀粉酶均低于对照组,差异有统计学意义(P均<0.05)。观察组的腹痛与腹痛缓解时间、住院天数明显短于对照组,差异有统计学意义(P均<0.05)。两组的不良反应发生率比较,差异无统计学意义(P>0.05)。结论注射用血塞通(冻干)联合生长抑素方案的整体效果更理想,有利于控制患者炎症反应,降低血淀粉酶、尿淀粉酶水平,缓解腹痛症状,缩短住院时间,安全可靠。Objective To explore the clinical effect of Xuesaitong combined with somatostatin in the treatment of acute pancreatitis.Methods Sixty patients with acute pancreatitis admitted to Dantu District People's Hospital of Zhenjiang,Jiangsu Province from January 2021 to June 2023 were non-randomly selected as the study subjects,and were divided into control group(treated with somatostatin)and observation group(treated with Xuesaitong combined with somatostatin)according to different treatment modalities,with 30 cases in each group.The clinical efficacy,in-flammatory factor levels,blood amylase and urine amylase,and recovery of the disease were compared between the two groups.Results The total clinical effective rate of the observation group was 93.33%,which was higher than that of the control group(73.33%),the difference was statistically significant(χ^(2)=4.320,P<0.05).The levels of serum in-flammatory factors,blood amylase and urine amylase in observation group were lower than those in control group,and the differences were statistically significant(all P<0.05).The abdominal pain,the time of abdominal pain relief and the days of hospitalization in the observation group were significantly shorter than those in the control group,and the differences were statistically significant(both P<0.05).There was no statistically significant difference in the inci-dence of adverse reactions between the two groups(P>0.05).Conclusion The overall effect of Xuesaitong(lyophilized)combined with somatostatin for injection is more ideal,which is beneficial to control the inflammatory response of pa-tients,reduce the levels of blood amylase and urine amylase,relieve the symptoms of abdominal pain,shorten the length of hospital stay,and is safe and reliable.

关 键 词：急性胰腺炎 生长抑素 注射用血塞通(冻干) 

分 类 号：R576[医药卫生—消化系统]