急性穿支动脉病变型脑梗死患者采用丁苯酞治疗的临床效果分析  

Clinical effect of butylphthalide in the treatment of patients with acute perforating artery disease-type cerebral infarction

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作  者:鲁进强 LU Jinqiang(Department of Neurology,Jiugang Hospital,Jiayuguan,Gansu,735100,China)

机构地区:[1]酒钢医院神经内外科,甘肃嘉峪关735100

出  处:《中国冶金工业医学杂志》2024年第4期375-376,共2页Chinese Medical Journal of Metallurgical industry

摘  要:目的分析丁苯酞对治疗急性穿支动脉病变型脑梗死患者的临床效果。方法选取2021年1月—2022年1月于我院治疗的160例急性穿支动脉病变型脑梗死患者,按照随机数字表法将其分为常规组和观察组,每组各80例。常规组采用常规治疗,观察组在常规治疗基础上联合丁苯酞治疗。对比两组的治疗效果、C反应蛋白(CRP)、血清同型半胱氨酸(Hcy)、神经功能缺损评分及日常生活能力。结果治疗后,观察组治疗总有效率高于常规组,两组比较差异有统计学意义(χ;2;=8.421,P<0.05);观察组的CRP、Hcy指标水平、神经功能缺损评分及日常生活能力评分均优于常规组,两组比较差异均有统计学意义(t=14.295、14.172、24.374、10.222,均P<0.05)。结论采用丁苯酞对急性穿支动脉病变型脑梗死患者进行治疗,能够有效改善患者的CRP、Hcy水平及神经功能缺损情况,同时能够提高患者的生活质量,其整体治疗效果及预后效果均得到了显著提升。ObjectiveTo observe and analyze the clinical effect of butylphthalide in patients with acute perforating artery disease-type cerebral infarction.Methods A total of 160 patients with acute perforating artery disease-type cerebral infarction from January 2021 to January 2022 in our hospital were randomly divided into the routine treatment group and observation treatment group,with 80 patients in each.The conventional group received standard treatment,while the observation group received butylphthalide in addition to the standard treatment.Treatment outcomes,C-reactive protein(CRP),serum homocysteine(Hcy)levels,neurological deficit scores,and daily living ability were compared between the groups.Results After treatment,the total effective rate in the observation group was higher than in the conventional group,with statistically significant differences(x2=8.421,P<0.05).The observation group also showed better results in CRP,Hcy levels,neurological deficit scores,and daily living ability scores,with statistically significant differences in all measures(t=14.295,14.172,24.374,10.222,all P<0.05).Conclusion The use of butylphthalide in the treatment of patients with acute perforating artery disease-type cerebral infarction can effectively improve the CRP,Hcy indexes,nurological deficits and improve the quality of life of the patients.The overall therapeutic effect and prognosis are obvious improvement.

关 键 词:急性穿支动脉疾病 脑梗死 丁苯酞 治疗效果 

分 类 号:R743.33[医药卫生—神经病学与精神病学]

 

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