羊乳低聚糖和其他家畜乳低聚糖研究进展  

Research Progress in Oligosaccharides in Goat and Non-goat Milk

作　　者：杨景博 赵晶晶 王雨奇 崔秀秀 曹宏芳 李春[1,4] 张国芳 刘丽波 YANG Jingbo;ZHAO Jingjing;WANG Yuqi;CUI Xiuxiu;CAO Hongfang;LI Chun;ZHANG Guofang;LIU Libo(College of Food Science,Northeast Agricultural University,Harbin 150000,China;Xi’an Baiyue Gaot Milk Corp.,Ltd.,Xi’an 710000,China;National Center of Technology Innovation for Dairy,Hohhot 010000,China;Heilongjiang Green Food Science Research Institute,Harbin 150000,China)

机构地区：[1]东北农业大学食品学院,黑龙江哈尔滨150000 [2]西安百跃羊乳集团有限公司,陕西西安710000 [3]国家乳业技术创新中心,内蒙古呼和浩特010000 [4]黑龙江省绿色食品科学研究院,黑龙江哈尔滨150000

出　　处：《食品科学》2024年第17期296-305,共10页Food Science

基　　金：国家乳业技术创新中心开放课题(2022-开放课题-12);黑龙江省自然科学基金重点项目(ZD2022C007);国家自然科学基金青年科学基金项目(32302043);乳品科学教育部重点实验室开放课题(KLDS-OF-202302);东北农业大学学术骨干项目(54916912);特质益生菌与新型发酵食品团队项目(54940912)。

摘　　要：母乳低聚糖(human milk oligosaccharides,HMOs)作为母乳中重要生物活性成分,现已成为婴幼儿配方奶粉热门营养强化剂。相比于人工合成的功能性低聚糖种类限制,分离提取动物乳源天然含有的低聚糖作为HMOs的替代产品具有可观的开发前景。其中羊乳低聚糖(goat milk oligosaccharides,GMOs)富含中性低聚糖,相比其他家畜乳低聚糖,其结构更类似于HMOs,具有替代HMOs的巨大潜力。然而现今乳低聚糖分离研究多集中于牛乳低聚糖,对其他家畜乳低聚糖研究较少,且家畜乳低聚糖结构和种类与HMOs存在差异,加之对于低聚糖结构与功能的联合分析较少,缺乏系统化的低聚糖结构与功能的研究,使得家畜乳低聚糖的开发利用受到限制。本文总结了家畜乳低聚糖的最新研究进展,并对GMOs的结构、检测方法和生理功能进行了重点介绍,同时通过对家畜乳低聚糖与HMOs的结构差异进行对比分析,以期为将来家畜乳低聚糖的开发应用提供理论支持。Human milk oligosaccharides(HMOs),an important bioactive ingredient in breast milk,have become a popular nutritional fortifier in infant formula.While only a limited variety of synthetic functional oligosaccharides is available now,naturally occurring oligosaccharides from animal milk are a promising substitute for HMOs.Goat milk oligosaccharides(GMOs)are rich in neutral oligosaccharides,which are more similar in structure to HMOs.However,most studies on the separation of milk oligosaccharides concentrate on bovine milk oligosaccharides,while little research has been done on milk oligosaccharides from animal species other than cows,and the structure and composition of animal milk oligosaccharides are different from those of HMOs.In addition,there are few systematic studies on the structures and functions of oligosaccharides,which limits the development and utilization of oligosaccharides in animal milk.This review summarizes the latest progress in research on oligosaccharides in animal milk with a focus on the structures,detection methods and physiological functions of GMOs,and it compares and analyzes the structural differences between animal milk oligosaccharides and HMOs.It is anticipated that this review can provide theoretical support for the development and application of animal milk oligosaccharides in the future.

关 键 词：羊乳低聚糖 家畜乳低聚糖 结构 功能 研究进展 

分 类 号：TS252[轻工技术与工程—农产品加工及贮藏工程]