炎症指标及肿瘤标志物预测间质性肺疾病合并肺癌的研究现状及应用  

Research status and application of inflammatory markers and tumor markers in predicting interstitial lung disease complicated with lung cancer

作　　者：屈小艳 赵明栋 向新玲 QU Xiaoyan;ZHAO Mingdong;XIANG Xinling(China Three Gorges University,Yichang,Hubei,443002,China;the Second People's Hospital of Yichang,Yichang,Hubei,443000,China)

机构地区：[1]三峡大学,湖北宜昌443002 [2]宜昌市第二人民医院,湖北宜昌443000

出　　处：《当代医学》2024年第13期184-189,共6页Contemporary Medicine

摘　　要：间质性肺疾病(ILD)以肺泡炎症反应、肺间质纤维化为主要病变,发病机制复杂,合并肺癌(LC)后治疗难度增加,发病率日益升高,预后差。早期识别ILD合并肺癌(ILD-LC)尤为重要。炎症指标及相关肿瘤标志物等检验指标与ILD-LC的发生发展密切相关,可在患者血液中被检测,能为早期诊断ILD-LC提供较为可靠的临床依据。本文旨在对炎症指标及肿瘤标志物预测ILD-LC研究现状及临床应用进行综述,以期为临床ILD-LC的早期诊断提供理论依据。Interstitial lung disease(ILD)is mainly characterized by alveolar inflammation and interstitial fibrosis,the pathogenesis is complex,and the treatment difficulty is increased after complicated with lung cancer(LC),the incidence is increasing,and the prognosis is poor.Therefore,early identification of ILD complicated with lung cancer(ILD-LC)is particularly important.Test indicators such as inflammatory indicators and related tumor markers are closely related to the occurrence and development of ILD-LC,and can be detected in patients'blood and other body fluids,providing a reliable clinical basis for the early diagnosis of patients with ILD-LC.This paper aims to review the research status and clinical application of inflammatory indicators and tumor markers in the prediction of ILD-LC,in order to provide theoretical basis for the early diagnosis of ILD-LC in clinic.

关 键 词：间质性肺疾病合并肺癌 中性粒细胞/淋巴细胞比值 血小板/淋巴细胞比值 肿瘤标志物 

分 类 号：R734.2[医药卫生—肿瘤]