经皮骨强化术治疗非小细胞肺癌溶骨性胸骨转移瘤  

Percutaneous bone augmentation enhancement treatment for osteolytic sternal metastases of non-small cell lung cancer

作　　者：李传海 贺呈祥 刘训伟 吕昌鹏 张梅[1] LI Chuanhai;HE Chengxiang;LIU Xunwei;LYU Changpeng;ZHANG Mei(Department of Thoracic Surgery,The 960th Hospital of the Joint Logistics Support Unit of the PLA,Jinan 250031,China;Oncology Department of South Campus,The 960th Hospital of the Joint Logistics Support Unit of the PLA,Jinan 250031,China;Department of Thoracic Surgery,Yuncheng County Chengxin Hospital,Heze 274700,China)

机构地区：[1]中国人民解放军联勤保障部队第960医院胸外科,山东济南250031 [2]中国人民解放军联勤保障部队第960医院南院肿瘤科,山东济南250031 [3]山东省郓城县诚信医院胸外科,山东菏泽274700

出　　处：《医学影像学杂志》2024年第8期124-126,共3页Journal of Medical Imaging

基　　金：国家自然科学基金项目(编号:81671799)。

摘　　要：目的 探讨经皮骨强化术(PBA)治疗非小细胞肺癌溶骨性胸骨转移瘤的疗效。方法 选取10例经病理证实的非小细胞肺癌溶骨性胸骨转移瘤行PBA的资料,回顾性分析手术治疗方法,采用术前、术后视觉模拟评分(VAS)、KPS评分评估临床疗效。采用SPSS 19.0统计学软件单因素方差分析,对所得数据进行统计学分析,以P<0.05为差异有统计学意义。结果 10例患者均顺利完成手术,术后1周,VAS评分由术前8.60±0.97降至术后2.70±0.67;KPS评分由术前31.00±9.94升至术后77.00±10.59,治疗前后两者差异均有统计学意义(P<0.05)。结论 PBA治疗非小细胞肺癌溶骨性胸骨转移瘤创伤小且安全,可获得良好的止痛效果,有效提高患者的生活质量。Objective To investigate the efficacy of percutaneous bone augmentation in the treatment of osteolytic sternal me-tastases of non-small cell lung cancer.Methods The data of 10 patients with pathology confirmed osteolytic sterna metastases of non-small cell lung cancer underwent percutaneous bone augmentation treatment were collected.The surgical treatment meth-ods were retrospectively analyzed.The clinical efficacy was evaluated by visual analogue scale(VAS)and karnofsky performance status(KPS)before and after operation.SPSS 19.0 statistical software was used to analyze the data by one-way ANOVA.P<0.05 indicated that the difference was significant.Results All the 10 patients were completed the operation successfully.The VAS score decreased from 8.60±0.97 to 2.70±0.67 after operation,and KPS score decreased from 31.00±9.94 to 77.00±10.59 af-ter operation,and the difference was statistically significant(P<0.05).Conclusion Percutaneous bone augmentation in the treatment of non-small cell lung cancer with osteolytic metastases of sternum can obtain good analgesic effect,improve the behav-ior ability of patients,with less trauma and safety,which can significantly improve the quality of life of patients.

关 键 词：胸骨转移瘤 经皮骨强化术 肺癌 介入性 放射学 

分 类 号：R738.1[医药卫生—肿瘤] R815[医药卫生—临床医学]