子午流注纳子法针刺联合西药治疗帕金森病合并不宁腿综合征患者30例随机对照试验  

Midnight-Noon Ebb-Low Acupuncture by Hour-Prescription of Points Combined with Western Medicine for Parkinson's Disease with Restless Legs Syndrome:A Randomized Controlled Trial

作　　者：李晓东[1] 吴秀玲[2] 蔡梅芝 石佳 LI Xiaodong;WU Xiuling;CAI Meizhi;SHI Jia(Tangshan Fengrun Traditional Chinese Medicine Hospital,Tangshan,064000;Tangshan Workers'Hospital)

机构地区：[1]唐山市丰润区中医医院,河北省唐山市064000 [2]唐山市工人医院

出　　处：《中医杂志》2024年第16期1681-1686,共6页Journal of Traditional Chinese Medicine

基　　金：河北省中医药管理局中医药类科学研究课题计划项目(2023204)。

摘　　要：目的观察子午流注纳子法针刺治疗帕金森病合并不宁腿综合征患者的临床疗效。方法将60例帕金森病合并不宁腿综合征患者随机分为对照组和治疗组,每组30例。对照组患者给予常规西药治疗,治疗组在对照组治疗基础上加用子午流注纳子法针刺治疗:大陵、中渚、阳陵泉、足三里、三阴交直刺,百会向后斜刺,均采用平补平泻手法;大都、太白当患者吸气时按照经脉循行的方向针刺进针,呼气时起针;针刺操作时间选巳时(9:00—11:00),每次留针30 min,每日1次,每周5次,共治疗4周。比较两组患者治疗前后国际不宁腿严重程度量表(IRLSS)评分、匹兹堡睡眠质量指数量表(PSQI)评分、帕金森病生活质量问卷(PDQ-39)评分、国际运动障碍学会统一帕金森病评定量表Ⅰ部分(MDS-UPDRSⅠ)评分;治疗后比较两组临床疗效。结果两组患者治疗后IRLSS评分、PSQI评分、PDQ-39评分、MDS-UPDRSⅠ评分均较本组治疗前下降(P<0.01),且治疗后治疗组均低于对照组(P<0.05或P<0.01)。治疗组临床疗效有效率为83.33%(25/30),高于对照组的60.00%(18/30)(P<0.05)。结论在常规西药治疗基础上加用子午流注纳子法针刺治疗帕金森病合并不宁腿综合征,可显著改善患者临床症状、睡眠障碍及生活质量,提高临床疗效。Objective To observe the clinical effectiveness of midnight-noon ebb-low acupuncture by hourprescription of points combined with western medicine for patients of Parkinson's disease with restless legs syndrome.Methods Sixty cases of Parkinson's disease with restless legs syndrome were divided into a control group and a treatment group randomly,with 30 cases in each group.The control group was given conventional western medicine treatment,and the treatment group was given the treatment of the control group with midnight-noon ebb-low acupuncture by hour-prescription of points based on Daling(PC 7),Zhongzhu(TE 3),Yanglingquan(GB 34),Zusanli(ST 36),and Sanyinjiao(SP 6)with perpendicular insertion,and Baihui(GV 20)with oblique insertion to the back,all of them used the manipulation of neutral reinforcement and reduction;Dudu(SP 2)and Taibai(SP 3)acupoints were inserted in accordance with the direction of the meridian travelling when the patients inhaled,and the needle was removed when exhaled;the time of acupuncture manipulation selected as Si time(9 AM-11 AM),the needle stay for 30 mins each time,once a day,5 times a week,a total of 4 weeks of treatment.The international restless legs severity scale(IRLSS),Pittsburgh sleep quality index(PSQI),Parkinson's disease quality of life questionnaire(PDQ-39),and the International Movement Disorder Society unified Parkinson's disease rating scale partⅠ(MDS-UPDRSⅠ)were compared before and after the treatment,and the clinical effectiveness of the two groups were compared after the treatment.Results IRLSS scores,PSQI scores,PDQ-39 scores and MDS-UPDRSⅠscores decreased in both groups after treatment compared to those before treatment(P<0.05 or P<0.01).After treatment,the total effective rate in the treatment group(83.3%,25/30)was higher than that in the control group(60%,18/30)(P<0.05).Conclusion Adding midnight-noon ebb-low acupuncture with hour-prescription of points on conventional western medicine treatment for Parkinson's disease with restless legs syndrome can signific

关 键 词：帕金森病 不宁腿综合征 针刺 子午流注 纳子法 随机对照试验 

分 类 号：R742.5[医药卫生—神经病学与精神病学]