盐酸倍他司汀联合常规药物治疗脑梗死伴头晕的临床效果分析  

Analysis on Clinical Effect of Betahistine Hydrochloride Combined with Conventional Drugs in Treatment of Cerebral Infarction with Dizziness

作　　者：孔顺利 Kong Shunli(Department of Neurology,Yanzhou District People's Hospital of Jining City,Jining 272100,Shandong Province,China)

机构地区：[1]济宁市兖州区人民医院神经内科,山东济宁272100

出　　处：《中国社区医师》2024年第21期57-59,共3页Chinese Community Doctors

摘　　要：目的:探讨盐酸倍他司汀联合常规药物治疗脑梗死伴头晕的临床效果。方法:选取2021年1月—2023年1月济宁市兖州区人民医院收治的80例脑梗死伴头晕患者作为研究对象,根据随机数字表法分为对照组和观察组,各40例。对照组应用常规药物治疗,观察组在对照组基础上应用盐酸倍他司汀治疗。比较两组日常生活活动能力、认知功能、神经功能、负面情绪及头晕症状。结果:治疗前,两组日常生活活动能力表(Barthel指数)、简易精神状态评价量表(MMSE)、美国国立卫生研究院卒中量表(NIHSS)评分比较,差异无统计学意义(P>0.05);治疗后,两组Barthel指数、MMSE评分高于治疗前,且观察组高于对照组,两组NIHSS评分均低于治疗前,且观察组低于对照组(P<0.05)。治疗前,两组焦虑自评量表(SAS)和抑郁自评量表(SDS)评分比较,差异无统计学意义(P>0.05);治疗后,两组SAS、SDS评分均低于治疗前,且观察组低于对照组(P<0.05)。治疗前,两组功能性评分、情绪性评分、躯体性评分、总分比较,差异无统计学意义(P>0.05);治疗后,两组功能性评分、情绪性评分、躯体性评分、总分均低于治疗前,且观察组低于对照组(P<0.05)。结论:盐酸倍他司汀联合常规药物治疗脑梗死合并头晕的临床效果较好,能够减轻患者头晕症状及负面情绪,提高患者日常生活活动能力,促进神经功能和认知功能的恢复。Objective:To explore the clinical effect of betahistine hydrochloride combined with conventional drugs in treatment of cerebral infarction with dizziness.Methods:A total of 80 patients with cerebral infarction and dizziness admitted to Yanzhou District People's Hospital of Jining City from January 2021 to January 2023 were selected as the study subjects.They were divided into control group and observation group with 40 cases in each group according to random number table method.The control group was treated with conventional drugs and the observation group was treated with betahistine hydrochloride on the basis of the control group.The activities of daily living,cognitive function,neurological function,negative mood and dizziness symptoms were compared between the two groups.Results:Before treatment,there was no significant difference between the two groups in the scores of activities of daily living scale(Barthel index),Mini-Mental State Examination(MMSE),and National Institutes of Health Stroke Scale(NIHSS)(P>0.05).After treatment,the Barthel index and MMSE scores in the two groups were higher than those before treatment,and these indexes in the observation group were higher than those in the control group,while the NIHSS scores in the two groups were lower than those before treatment,and this index in the observation group was lower than that in the control group(P<0.05).Before treatment,there was no significant difference in the scores of Self-Rating Anxiety Scale(SAS) and Self-Rating Depression Scale(SDS) between the two groups(P>0.05).After treatment,the SAS and SDS scores in the two groups were lower than those before treatment,and the scores in the observation group were lower than those in the control group(P<0.05).Before treatment,there was no significant difference in functional scores,emotional scores,somatic scores and total scores between the two groups(P>0.05).After treatment,the functional scores,emotional scores,somatic scores and total scores in the two groups were lower than those before treatm

关 键 词：脑梗死 头晕 盐酸倍他司汀 

分 类 号：R743.33[医药卫生—神经病学与精神病学]