功能性近红外光谱脑成像技术在轻度认知障碍诊疗中的应用进展  

Usage of functional near-infrared spectroscopy in diagnosis and treatment of mild cognitive impairment

作　　者：濮正平 黄虹娜 崔东红[2] Pu Zhengping;Huang Hongna;Cui Donghong(Department of Psychogeriatrics,Affiliated Mental Health Center of Jiaring University(Kangci Hospital of Jiaring),Jiaiang 314500,China;Shanghai Key laboratory of Psychotic Disorders,Shanghai Mental Health Center,Shanghai Jiao Tong University School of Medicine,Shanghai 201108,China)

机构地区：[1]嘉兴学院附属精神卫生中心(嘉兴市康慈医院)老年精神科,嘉兴314500 [2]上海交通大学附属精神卫生中心上海市重性精神病重点实验室,上海201108

出　　处：《中华老年医学杂志》2024年第8期1072-1078,共7页Chinese Journal of Geriatrics

基　　金：国家重点研发计划(2017YFC0909200);浙江省医药卫生科技计划项目(2023XY053);浙江省中医药科技计划项目(2023ZL703)。

摘　　要：轻度认知障碍(MCI)进展为痴呆的风险较高,目前仍然缺乏准确度高、适宜推广的MCI筛查技术。近年来的研究显示,功能性近红外光谱(fNIRS)技术具有筛查MCI的潜力,且可用于干预措施的疗效评估。本文从概念背景、认知功能评估的运用、MCI诊断与筛查、疗效评估、存在的不足等角度综述了fNIRS在MCI诊疗方面的运用与前景,以期为后续的临床研究与转化提供思路与参考。Mild cognitive impairment(MCI)carries a high risk of progressing to dementia,yet there is a lack of specific and accurate screening techniques.Recent research suggests that functional near-infrared spectroscopy(fNIRS)holds significant potential for screening MCI and evaluating the effectiveness of therapeutic interventions.Therefore,this paper aims to review the application and future prospects of fNIRS in diagnosing and treating MCI.The review covered various aspects including the background,assessment of cognitive function,screening methods for MCI,evaluation of therapeutic efficacy,and limitations.The findings of this review can serve as a valuable reference for futureclinical studies.

关 键 词：功能性近红外光谱 轻度认知障碍 认知功能 

分 类 号：R749.1[医药卫生—神经病学与精神病学]