Psychometric validation of the Chinese version of the dry eye-related quality-of-life score questionnaire  

作　　者：Yu-Wen Liu Shu-Jia Guo Jia-Ni Li Yu-Ting Zhang Wei-Jie Ouyang Yu-Qian Wang Cai-Hong Huang Yi Liao Jiaoyue Hu Zuguo Liu 

机构地区：[1]Xiamen University Affiliated Xiamen Eye Center,Fujian Provincial Key Laboratory of Ophthalmology and Visual Science,Fujian Engineering and Research Center of Eye Regenerative Medicine,Eye Institute of Xiamen University,School of Medicine,Xiamen University,Xiamen 361005,Fujian Province,China [2]Department of Ophthalmology,Xiang’an Hospital of Xiamen University,Xiamen 361005,Fujian Province,China [3]Department of Ophthalmology,the First Affiliated Hospital of University of South China,Hengyang 421001,Hunan Province,China

出　　处：《International Journal of Ophthalmology(English edition)》2024年第9期1614-1620,共7页国际眼科杂志（英文版）

基　　金：Supported by the National Natural Science Foundation of China(No.82271054,No.U20A20363,No.81900825);Santen Pharmaceutical(China)Co.,Ltd.

摘　　要：AIM:To psychometrically validate the Chinese version of the dry eye-related quality-of-life score questionnaire(DEQSCHN)among Chinese patients with dry eye.METHODS:This study involved 231 participants,including 191 with dry eye disease(DED)comprising the dry eye disease group,and 40 healthy participants forming the control group.Participants were required to complete the DEQS-CHN,and Chinese dry eye questionnaire and undergo clinical tests including the fluorescein breakup time(FBUT),corneal fluorescein staining(CFS),and Schirmer I test.To assess the internal consistency and retest reliability,Cronbach’sαand the intraclass correlation coefficient(ICC)were employed.Content validity was assessed by item-level content validity index(ICV)and an average scale-level content validity index(S-CVI/Ave).Construct validity was assessed by confirmatory factor analysis.The concurrent validity was assessed by calculating correlations between DEQS-CHN and Chinese dry eye questionnaire.Discriminative validity was evaluated through nonparametric tests,with receiver operating characteristic(ROC)curve serving as conclusive indicators of the questionnaire’s distinguishing capability.RESULTS:The Cronbach’sαcoefficients for frequency and degree of ocular symptoms,impact on daily life,and summary score were 0.736,0.704,0.811,0.818,0.861,and 0.860,respectively,and the ICC were 0.611,0.677,0.715,0.769,0.711,and 0.779,respectively.All I-CVI scores ranged from 0.833 to 1.000,with an S-CVI/Ave of 0.956.Confirmatory factor analysis results exhibited a wellfitting model consistent with the original questionnaire[χ^(2)/df=2.653,incremental fit index(IFI)=0.924,comparative fit index(CFI)=0.924,Tucker-Lewis index(TLI)=0.909,and root mean square error of approximation(RMSEA)=0.065].There was a moderate positive correlation between the DEQS-CHN and the Chinese dry eye questionnaire(r^(2)=0.588).The dry eye group demonstrated significantly higher scores compared to the control group,and the area under the curve(AUC)value was 0.8092.CONCLUS

关 键 词：dry eye QUALITY-OF-LIFE QUESTIONNAIRE 

分 类 号：R777.34[医药卫生—眼科]