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作 者:谢豪 康亮[1] Xie Hao;Kang Liang(Department of Colorectal Surgery,the Sixth Affiliated Hospital,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases,the Sixth Affiliated Hospital,Sun Yat-sen University,Biomedical Innovation Center,the Sixth Affiliated Hospital,Sun Yat-sen University,Guangzhou 510655,China)
机构地区:[1]中山大学附属第六医院结直肠外科、广东省结直肠盆底疾病研究重点实验室、广州市黄埔区中山六院生物医学创新研究院,广州510655
出 处:《中华胃肠外科杂志》2024年第8期857-861,共5页Chinese Journal of Gastrointestinal Surgery
基 金:国家临床重点专科;中山大学临床医学研究5010计划项目(2016005)。
摘 要:直肠癌手术极具技术挑战性,并与胃肠道、泌尿系统和性功能的重大改变以及生活质量下降有关。直肠癌的治疗发展迅速,新数据不断涌现。对比2020年版美国结直肠外科医师协会直肠癌诊疗临床实践指南,2023年增补版指南对直肠癌治疗中长久以来及新近出现的问题提供了新的循证推荐,包括上段直肠癌治疗、全程新辅助治疗、新辅助后临床完全缓解患者的等待观察策略、经肛全直肠系膜切除术的安全性。Surgery for rectal cancer is highly technically challenging and often results in significant changes to the gastrointestinal,urinary,and sexual function,with impact on quality of life.The treatment of rectal cancer has advanced rapidly,with new data continually emerging.The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Rectal Cancer 2023 Supplement introduces new evidence-based recommendations addressing both longstanding and emerging issues,compared to the 2020 edition.These updates include treatment strategies for upper rectal cancer,the use of total neoadjuvant therapy,the adoption of a watch-and-wait strategy for patients who achieve a clinical complete response after neoadjuvant therapy,and the safety of transanal total mesorectal excision.
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