巩膜镜矫正屈光不正的安全性  

Safety of scleral contact lenses in correcting ametropia

作　　者：闻郁 刘东伟[2] 陶黎明[2] WEN Yu;LIU Dongwei;TAO Liming(The Second Clinical Medical College of Anhui Medical University,Hefei 230601,Anhui Province,China;Department of Ophthalmology,The Second Affiliated Hospital of Anhui Medical University,Hefei 230601,Anhui Province,China)

机构地区：[1]安徽医科大学第二临床医学院,安徽省合肥市230031 [2]安徽医科大学第二附属医院眼科,安徽省合肥市230601

出　　处：《眼科新进展》2024年第9期719-723,共5页Recent Advances in Ophthalmology

基　　金：安徽省重点研究与开发计划项目(编号:2022j11020013)。

摘　　要：目的 探讨硬性巩膜接触镜在矫正屈光不正方面的安全性。方法 前瞻性研究,选取96例(192眼)近视患者(度数-20.00~0 D,散光度数0~3.50 D)为研究对象,分为试验组(配戴硬性巩膜接触镜)和对照组[配戴硬性角膜接触镜(RGP)],每组48例,分别于戴镜前、戴镜当天、戴镜后1周、戴镜后1个月及戴镜后3个月时检测并比较两组患者眼部相关参数指标[最佳矫正视力、角膜内皮细胞密度、六角形细胞比率、泪膜破裂时间(BUT)、眼压、角膜荧光素染色评分、结膜充血及睫状充血评分],观察是否出现眼部异常改变。结果 戴镜前至戴镜3个月期间,两组患者最佳矫正视力均≥1.00;戴镜后3个月时,与戴镜前比较,试验组患者角膜内皮细胞密度轻微下降,六角形细胞比率轻微上升,但差异均无统计学意义(均为P>0.05);戴镜前及戴镜后3个月时,试验组角膜内皮细胞密度及六角形比率均较对照组稍高,但差异均无统计学意义(均为P>0.05)。戴镜前、戴镜当天、戴镜后1周、戴镜后1个月及戴镜后3个月时,试验组与对照组患者BUT比较,差异均无统计学意义(均为P>0.05)。戴镜前、戴镜当天、戴镜后1周、戴镜后1个月及戴镜后3个月试验组与对照组患者眼压比较,差异均无统计学意义(均为P>0.05)。戴镜前及戴镜后3个月时,两组患者角膜荧光染色评级、结膜充血及睫状充血评级比较,差异均无统计学意义(均为P>0.05)。戴镜后3个月时,试验组患者均未出现结膜及角膜水肿等异常改变。结论 硬性巩膜接触镜与RGP具有一致的安全性与矫正屈光不正的有效性,值得推广及应用。Objective To investigate the safety of rigid scleral contact lenses in correcting ametropia.Methods A total of 96 patients(192 eyes)with myopia between-20.00 and 0 D and astigmatism between 0 and 3.5 D were included in this perspective study.They were divided into an experimental group(wearing rigid scleral contact lenses)and a control group[wearing rigid corneal contact lenses(RGP)],with 48 patients in each group.Eye indicators including best corrected visual acuity(BCVA),corneal endothelial cell density,hexagonal cell ratio,tear film break-up time(BUT),intraocular pressure(IOP),corneal fluorescence staining score,conjunctival congestion score,and ciliary congestion score were measured and compared between the two groups before wearing,on the day of wearing,and 1 week,1 month,and 3 months after wearing lenses,and eye changes were observed.Results The BCVA of patients in the two groups was grea\|ter than or equal to 1.00 before wearing lenses and within 3 months after wearing lenses.Compared with before wearing lenses,the corneal endothelial cell density in the experimental group slightly decreased,and the hexagonal cell ratio slightly increased at 3 months after wearing lenses,but the differences were not statistically significant(both P>0.05).Before wearing lenses and at 3 months after wearing lenses,the corneal endothelial cell density and the hexagonal cell ratio in the experimental group were slightly higher than those in the control group,but the differences were not statistically significant(both P>0.05).There were no significant differences in BUT and IOP between the experimental group and the control group before wearing,on the day of wearing,and 1 week,1 month,and 3 months after wearing lenses(all P>0.05).There were no significant differences in corneal fluorescence staining score and conjunctival and ciliary congestion ratings between the experimental group and the control group before wearing lenses and at 3 months after wearing lenses(all P>0.05).At 3 months after wearing lenses,no conjunctival or co

关 键 词：硬性巩膜接触镜 硬性角膜接触镜 屈光不正 安全性 眼表指标 

分 类 号：R778.1[医药卫生—眼科]