干眼的局部药物治疗研究进展  

Advances in topical drug therapy for dry eye

作　　者：黄希帆 何敏[2] 耿婉清 万青清 HUANG Xifan;HE Min;GENG Wanqing;WAN Qingqing(Shanxi Medical University,Taiyuan 030001,Shanxi Province,China;Department of Ophthalmology,the Second Hospital of Shanxi Medical University,Taiyuan 030001,Shanxi Province,China)

机构地区：[1]山西医科大学,山西省太原市030001 [2]山西医科大学第二医院眼科,山西省太原市030001

出　　处：《眼科新进展》2024年第9期753-756,共4页Recent Advances in Ophthalmology

基　　金：山西省重点研发项目(编号:201903D321121)。

摘　　要：干眼是一种由泪膜和眼表异常所引起的多因素疾病,临床表现为不同程度的畏光、瘙痒、烧灼感、视疲劳、视力波动等不适感。干眼如果未及时治疗,严重者可引起眼部炎症、角膜溃疡及视力损伤等。局部药物治疗为目前干眼最简便、常用的治疗方法,随着我们对干眼发病机制的进一步认识,多种新的局部药物也应用于临床。本文就干眼的局部药物治疗进展进行综述。Dry eye is a multifactorial disease caused by abnormal tear film and ocular surface.The clinical manifestations include photophobia,pruritus,burning sensation,visual fatigue,vision fluctuation,and other eye discomfort.If not treated in time,severe dry eye may cause eye inflammation,corneal ulcers,visual impairment,and other complications.Topical drug therapy is currently the simplest and most commonly used treatment for dry eye.With the further exploration of dye eye’s pathogenesis,many new topical drugs have been used in clinical practice.This article reviews the advances in the topical drug therapy for dry eye.

关 键 词：干眼 药物治疗 研究进展 

分 类 号：R777.34[医药卫生—眼科]