非吸烟人群肺癌研究进展  

Research progress of lung cancer in the non-smoking population

作　　者：刘苗艳 杨朝婷 高瑞 张艰 Liu Miaoyan;Yang Chaoting;Gao Rui;Zhang Jian(Xi′an Medical University,Xi′an 710021,China;Department of Respiratory Medicine,People′s Hospital of Northwest University(Xi′an Fourth Hospital),Xi′an 710004,China)

机构地区：[1]西安医学院,西安710021 [2]西北大学附属人民医院(西安市第四医院)呼吸内科,西安710004

出　　处：《国际呼吸杂志》2024年第8期984-988,共5页International Journal of Respiration

基　　金：陕西省自然科学基础研究计划(2024JC-ZDXM-45)

摘　　要：肺癌是全球癌症最常见的死亡原因。多数肺癌的发生与吸烟状态密切相关,但约有10%~25%的肺癌患者从未吸烟。随着研究的深入,人们发现非吸烟人群肺癌(LCINS)是一种独特的疾病实体,最常见于女性腺癌患者。因此了解LCINS的发生、发展对于这类患者的临床管理和治疗尤为重要。本文就近年来LCINS的流行病学、危险因素、特征、治疗和预后研究进展进行综述。Lung cancer is the most common cause of cancer death worldwide.Carcinogenesis of the majority of lung cancer is closely related to smoking status,but about 10%-25%of lung cancer patients are non-smokers.With the deep mining of lung cancer research,lung cancer in never smokers(LCINS)has been found as a unique entity,which is most commonly found in female adenocarcinoma patients.Therefore,understanding the occurrence and development of LCINS is particularly important for the clinical management and treatment of this population.This article described the progress of research on the epidemiology,risk factors,characteristics,treatment and prognosis of LCINS in recent years.

关 键 词：肺肿瘤 非吸烟者 流行病学 危险因素 预后 

分 类 号：R734.2[医药卫生—肿瘤]