宫颈HSIL锥切术后切缘阳性相关因素分析  

Analysis of correlation factors of positive margin after HSIL conectomy

作　　者：汪志辉[1] 玉珍 姚冬花 Wang Zhihui;Yu Zhen;Yao Donghua(Department of Obstetrics and Gynecology,The Third Affiliated Hospital of Guangzhou Medical University,Guangzhou 5101502,China;Nyingchi City People's Hospital Obstetrics and Gynecology,Nyingchi 680000,China)

机构地区：[1]广州医科大学附属第三医院妇产科,广东广州510150 [2]林芝市人民医院妇产科,西藏林芝680000

出　　处：《西藏医药》2024年第4期39-41,共3页Tibetan Medicine

摘　　要：目的目的分析宫颈HSIL锥切术后切缘阳性的相关因素。方法方法回顾性分析2016年1月~2020年12月病理确诊的宫颈HSIL并行宫颈锥切的患者776例。分析治疗方式、年龄、累及腺体、HPV感染、多点病变与切缘阳性的相关性。结果结果776例患者锥切术后切缘阳性143例(18.32%);单因素分析显示宫颈HSIL锥切术后切缘阳性与LEEP手术(P<0.05)、累及腺体(P<0.01)、多点病变(P<0.05)有关,与HPV感染(P>0.05)、年龄(P>0.05)无关;多因素回归分析显示LEEP手术、累及腺体及宫颈多点病变是宫颈HSIL锥切术后切缘阳性的独立危险因素(P<0.05)。结论结论LEEP手术、累及腺体及宫颈多点病变是宫颈HSIL锥切术后切缘阳性的高危因素,在治疗上要引起重视。Objective To analyze the related causes of high grade squamous intraepithelial lesion(HSIL)with positive margin af-ter cervical conization.Methods From January 2016 to December 2020,776 patients with cervical HSIL and conectomy were retro-spectively analyzed.The correlation of treatment,age,glands involved,HPV infection,multipoint lesions and positive incisal mar-gin were analyzed.Results Of 776 patients,143(18.32%)had positive margins after cone resection.Univariate analysis showed that positive incisal margin after HSIL conectomy was associated with LEEP surgery(P<0.05),involved glands(P<0.01)and multi-point lesions(P<0.05),but not HPV infection(P>0.05)or age(P>0.05).Multivariate regression analysis showed that LEEP sur-gery,glandular involvement and multiple cervical lesions were independent risk factors for positive incisal margin after HSIL conec-tomy(P<0.05).Conclusion LEEP surgery,glandular involvement and cervical multipoint lesions are high risk factors for positive margin after HSIL conectomy.Attention should be paid to the treatment.

关 键 词：宫颈HSIL 切缘阳性 危险因素 

分 类 号：R737.33[医药卫生—肿瘤]