Pathological changes in the brain after peripheral burns  

作　　者：Jigang Chen Danfeng Zhang Junhui Zhang Yanni Wang 

机构地区：[1]Department of Burn and Plastic Surgery,Beijing Children’s Hospital,Capital Medical University,National Center for Children’s Health,Beijing 100045,China [2]Department of Neurosurgery,Shanghai Changzheng Hospital,Second Military Medical University,Shanghai 200003,China [3]Institute of Burns Research,State Key Laboratory of Trauma,Burns and Combined Injury,Southwest Hospital,Third Military Medical University,Chongqing 400038,China [4]Department of Geriatric Oncology,Department of Palliative care,Department of Clinical nutrition,Chongqing University Cancer Hospital,No.181 Hanyu Road,Shapingba District,Chongqing 400030,P.R.China

出　　处：《Burns & Trauma》2023年第1期176-187,共12页烧伤与创伤（英文）

基　　金：Natural Science Foundation of China(82101433).

摘　　要：Brain injuries are common complications in patients with thermal burns and are associated with unpleasant outcomes.In clinical settings,it was once believed that brain injuries were not major pathological processes after burn,at least in part due to the unavailability of specific clinical manifestations.Burn-related brain injuries have been studied for more than a century,but the underlying pathophysiology has not been completely clarified.This article reviews the pathological changes in the brain following peripheral burns at the anatomical,histological,cytological,molecular and cognitive levels.Therapeutic indications based on brain injury as well as future directions for research have been summarized and proposed.

关 键 词：BURN Brain injuries Pathological changes Blood-brain barrier INFLAMMATION 

分 类 号：R644[医药卫生—外科学]