超声弹性成像技术联合血清甲胎蛋白、γ-谷氨酰转肽酶检验诊断肝脏良恶性肿瘤的价值  

The value of ultrasound elastography combined with serum alpha fetoprotein and γ-glutamyl transpeptidase assay in the diagnosis of benign and malignant tumors of the liver

作　　者：张英萍 钟于丽 ZHANG Yingping;ZHONG Yuli(Department of Ultrasonography,Ganzhou People’s Hospital,Ganzhou 341000,China)

机构地区：[1]赣州市人民医院超声科,赣州341000

出　　处：《上海医药》2024年第15期36-39,共4页Shanghai Medical & Pharmaceutical Journal

摘　　要：目的:分析超声弹性成像技术联合血清甲胎蛋白(AFP)、γ-谷氨酰转肽酶(GGT)检验诊断肝脏良恶性肿瘤的应用价值。方法:选取肝脏恶性病变(恶心组)及良性病变(良性组)患者各40例,均进行超声弹性成像检查,测定血清AFP、GGT水平,分析其对肝脏良恶性诊断的价值。结果:恶性组弹性硬度评分及血清AFP、GGT水平均高于良性组(P<0.05)。超声弹性成像弹性硬度评分、S1S2指数联合血清AFP和GGT检验诊断肝脏良恶性肿瘤的敏感度为100.00%,特异度为97.50%,均高于单一指标(P<0.05)。结论:超声弹性成像联合血清AFP、GGT检验诊断肝脏良恶性肿瘤的临床价值高。Objective:To analyze the application value of the combination of ultrasound elastography with serum alpha fetoprotein(AFP)andγ-glutamyl transpeptidase(GGT)assay in the diagnosis of benign and malignant tumors of the liver.Methods:Forty patients with malignant liver lesions(malignant group)and 40 patients with benign liver lesions(benign group)were selected for ultrasound elastography examination,and their serum AFP and GGT levels were determined to analyze their diagnostic value for benign and malignant liver lesions.Results:The elastic hardness scores and the serum AFP and GGT levels were higher in the malignant group than the benign group(P<0.05).The sensitivity and specificity of ultrasound elastography elastic hardness scores,S1S2 index combined with serum AFP and GGT levels for the diagnosis of benign and malignant tumors of the liver were 100.00%and 97.50%,which were all higher than the single index(P<0.05).Conclusion:Ultrasound elastography combined with serum AFP and GGT levels has high clinical value in the diagnosis of benign and malignant tumors of the liver.

关 键 词：超声弹性成像 甲胎蛋白 γ- 谷氨酰转肽酶 肝脏良恶性肿瘤 

分 类 号：R730.41[医药卫生—肿瘤] R735.7[医药卫生—临床医学]