消化道肿瘤肝转移介入治疗的临床疗效观察  

Clinical Efficacy Observation of Interventional Therapy for Liver Metastasis of Digestive Tract Tumors

作　　者：路佩佩 LU Peipei(Tumor Minimally Invasive and Comprehensive Interventional Ward,Henan University First Affiliated Hospital,Kaifeng Henan 475001,China)

机构地区：[1]河南大学第一附属医院肿瘤微创与综合介入病区,河南开封475001

出　　处：《临床研究》2024年第9期86-88,共3页Clinical Research

摘　　要：目的本研究旨在探讨消化道肿瘤肝转移的介入治疗临床疗效及患者1年、3年、5年生存率情况。方法本项研究选取了河南大学第一附属医院2013年2月至2018年2月期间收治的192名消化道肿瘤肝转移患者,通过回顾性分析这些患者的临床记录,观察并分析了不同消化系统肿瘤肝转移患者接受介入治疗后的临床疗效和1年、3年、5年存活率。结果不同原发肿瘤类型患者完全缓解比例、部分缓解比例、病情稳定比例、病情恶化比例及治疗有效率比较,差异有统计学意义(P<0.05)。其中胃肿瘤患者治疗有效率高于结肠肿瘤患者及胰腺肿瘤患者,结肠肿瘤患者治疗有效率高于胰腺肿瘤患者,差异有统计学意义(P<0.05)。不同原发肿瘤类型患者1年、3年、5年生存率比较,差异有统计学意义(P<0.05)。其中胃肿瘤1年、3年、5年生存率高于结肠肿瘤患者及胰腺肿瘤患者,结肠肿瘤患者1年、3年、5年生存率高于胰腺肿瘤患者,差异有统计学意义(P<0.05)。结论对于无法通过手术根治的消化道肿瘤肝转移患者可采用介入疗法,其对于不同肿瘤类型表现有一定差异,其中胰腺肿瘤相较于结肠肿瘤及胃肿瘤临床表现较差,胃肿瘤肝转移患者的临床表现最优。临床医生在进行介入治疗时仍需谨慎,根据患者的具体情况选择适当的治疗方案,避免因过量化疗药物使用或过度栓塞导致肝功能损伤。Objective This study aims to investigate the clinical efficacy of interventional therapy for liver metastasis of digestive tract tumors and the 1-year,3-year,and 5-year survival rates of patients.Methods This study selected 192 patients with liver metastasis of digestive tract tumors who were admitted to the First Affiliated Hospital of Henan University from February 2013 to February 2018.Through retrospective analysis of these patients’clinical records,the clinical efficacy and 1-year,3-year,and 5-year survival rates of patients with liver metastasis from different digestive system tumors who received interventional therapy were observed and analyzed.Results There were statistically significant differences(P<0.05)in the complete remission rate,partial remission rate,stable disease rate,progressive disease rate,and treatment efficacy rate among patients with different primary tumor types.Among them,the treatment efficacy rate of gastric tumor patients was higher than that of colon tumor patients and pancreatic tumor patients,and the treatment efficacy rate of colon tumor patients was higher than that of pancreatic tumor patients,with statistically significant differences(P<0.05).There were statistically significant differences(P<0.05)in the 1-year,3-year,and 5-year survival rates among patients with different primary tumor types.Among them,the 1-year,3-year,and 5-year survival rates of gastric tumor patients were higher than those of colon tumor patients and pancreatic tumor patients,and the 1-year,3-year,and 5-year survival rates of colon tumor patients were higher than those of pancreatic tumor patients,with statistically significant differences(P<0.05).Conclusion Interventional therapy can be used for patients with liver metastasis of digestive tract tumors who cannot be cured by surgery.There are certain differences in its efficacy for different tumor types,with pancreatic tumors showing poorer clinical performance compared to colon tumors and gastric tumors,and gastric tumor liver metastasis patients showi

关 键 词：消化道 肿瘤 肝转移 介入治疗 

分 类 号：R735[医药卫生—肿瘤]