原发性阴茎恶性黑色素瘤1例报告  

Primary malignant melanoma of penis:a case report

作　　者：陈峙橦 黄龙 陈小彬 周晓峰[3] 陈爽 程文龙 陈国俊[1] Chen Zhitong;Huang Long;Chen Xiaobin;Zhou Xiaofeng;Chen Shuang;Cheng Wenlong;Chen Guojun(Department of Urology,Afiliated Hospital of Qinghai University,Xining 81000,China;Department of Hepatobiliary and Pancreatic Surgery,Afiliated Hospital of Qinghai University,Xining 810000,China;Department of Pathology,Affiliated Hospital of Qinghai University,Xining 810000,China)

机构地区：[1]青海大学附属医院泌尿外科,西宁810000 [2]青海大学附属医院肝胆胰外科,西宁810000 [3]青海大学附属医院病理科,西宁810000

出　　处：《中华泌尿外科杂志》2024年第8期633-634,共2页Chinese Journal of Urology

摘　　要：本文报道青海大学附属医院收治的1例阴茎原发性恶性黑色素瘤患者,56岁,因发现阴茎肿物1个月入院。查体:尿道外口下方近系带处可见大小约1.5cm×2.0cm不规则菜花样肿物,表面覆盖黄色坏死组织,触痛阳性;左、右侧腹股沟区可触及数枚包块,触痛阳性。实验室检查未见异常。头、胸部、腹部、盆腔CT检查未见明显异常。阴茎肿物活检病理提示恶性黑色素瘤。右侧腹股沟区淋巴结穿刺活检病理结果考虑局部炎症反应。结合患者病史、查体、影像学检查和淋巴结穿刺结果诊断为原发性阴茎恶性黑色素瘤。行阴茎部分切除术,术后病理诊断为恶性黑色素侵犯表皮伴溃疡。术后随访9个月无局部复发和转移。This article reports a case data of primary malignant melanoma of the penis admitted to the Affiliated Hospital of Qinghai University.A 56-year-old patient was admitted to the hospital 1 month after the discovery of a penile mass.Physical examination:An irregular cauliflower-like mass about 1.5 cm×2.0 cm in size was seen below the external urethral orifice,covered with yellow necrotic tissue,and tenderness was positive.Several nodes were palpable in the left and right groin areas,tenderness positive.Laboratory examination showed no abnormality.The CT examination of head,chest,abdomen and pelvis showed no obvious abnormality.The biopsy of the penile mass showed malignant melanoma of the penis.The pathological results of biopsy of the right inguinal lymph node considered local inflammation.Combined with the patient's medical history,physical examination,imaging examination and lymph node biopsy results,a diagnosis of primary penile malignant melanoma was made.Partial penile resection was performed,and the postoperative pathological diagnosis was malignant melanin invasion of the epidermis with ulceration.There was no local recurrence and metastasis during the 9-month follow-up.

关 键 词：黑色素瘤 原发性阴茎恶性黑色瘤 手术 免疫组化 

分 类 号：R737.27[医药卫生—肿瘤]