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作 者:沈曼曼 包向阳 尹敏[1] SHEN Manman;BAO Xiangyang;YIN Min(Department of Radiotherapy,Pizhou People's Hospital,Pizhou 221300,Jiangsu,China)
机构地区:[1]邳州市人民医院放疗一科,江苏邳州221300
出 处:《系统医学》2024年第14期156-158,173,共4页Systems Medicine
摘 要:目的探究调强放疗技术在乳腺癌放疗中的临床价值。方法非随机选取邳州市人民医院放疗科于2021年1月—2023年10月期间收治的78例乳腺癌放疗患者为研究对象开展研究,根据不同放疗技术方式进行分组,接受常规放疗技术治疗患者为对照组(n=39),接受调强放疗技术治疗患者为观察组(n=39),连续治疗5周后对比两组局控率、肺受量、不良反应发生情况。结果治疗5周后,观察组局控率略高于对照组,但差异无统计学意义(P>0.05)。观察组V50、V40、V30、V20、V10、V5肺指数均较对照组低,差异有统计学意义(P均<0.05)。观察组放射性皮炎发生率为5.13%(2/39)、放射性食管炎发生率为2.56%(1/39),低于对照组的20.51%(8/39)、20.51%(8/39),差异有统计学意义(χ^(2)=4.129,4.522,P均<0.05)。结论调强放疗技术在乳腺癌治疗中的效果与常规放疗相当,但调强放疗技术安全性更高,有助于减轻肺损伤。Objective To explore the clinical value of intensity modulated radiotherapy in breast cancer radiotherapy.Methods A total of 78 breast cancer radiotherapy patients admitted to the Radiotherapy Department of Pizhou People's Hospital from January 2021 to October 2023 were non-randomly selected as the study objects.According to different radiotherapy techniques,the patients treated with conventional radiotherapy were divided into control group(n=39)and those treated with intensity modulated radiotherapy were divided into observation group(n=39).After 5 weeks of continuous treatment,the local control rate,lung receptivity and adverse reactions were compared between the two groups.Results After 5 weeks of treatment,the local control rate of observation group was slightly higher than that of control group,but the difference was not statistically significant(P>0.05).The lung indices of V50,V40,V30,V20,V10 and V5 in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).The incidence of radiation dermatitis in the observation group was 5.13%(2/39)and 2.56%(1/39),which were lower than 20.51%(8/39)and 20.51%(8/39)in the control group,and the differences were statistically significant(χ^(2)=4.129,4.522,both P<0.05).Conclusion Intensity modulated radiotherapy has the same effect as conventional radiotherapy in the treatment of breast cancer,but it is safer and helps to reduce lung damage.
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