Bibliometric analysis of 100 most-cited papers on Icariin  

作　　者：Lin Mao Yi-Feng Shen Kun Zhu Jun-Long Zhu Xiao-Peng Huang De-Gui Chang Yao-Dong You Dong-Dong Yang 

机构地区：[1]Department of Continuing Education,Sichuan Integrative Medicine Hospital,Chengdu 610042,China [2]TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province,Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610032,China [3]School of Clinical Medicine,Chengdu University of Traditional Chinese Medicine,Chengdu 610032,China [4]Department of Neurology,Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610032,China

出　　处：《Pharmacology Discovery》2024年第3期36-47,共12页

基　　金：supported by the Natural Science Foundation of Sichuan Province(2023NSFSC1799);the Science and Technology Development Fund of the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine(21ZS05,23YY07).

摘　　要：Icariin is the most prevalent component of the medicinal herb Herba Epimedii.Icariin exhibits many medicinal properties,including anti-cancer impact and osteoprotective and neuroprotective effects.The goal of this study was to use bibliometric analysis to find and describe the top 100 papers about Icariin that had received the most citations.The Science Citation Index-Expanded(SCI-E)of the Web of Science Core Collection was used to find publications on Icariin(WoSCC).Descriptive analysis was conducted using VOSviewer software.There were 1473 articles about Icariin in all.The top 100 papers were published between 1996 and 2024 and received citations in the range of 55 to 390.The country that has contributed the most to Icariin research is China(84).The most productive institution was Fudan University.The most published journal was Phytomedicine.The research hotspots of Icariin mainly focus on the following aspects:research on Icariin treatment of sex hormone-related osteoporosis and erectile function;The effect of Icariin on cells by regulating oxidative stress,apoptosis,and proliferation;the mechanism of Icariin in the treatment of cancer;the neuroprotective effect of Icariin in central nervous diseases,such as Alzheimer's disease,Parkinson's disease,and depression.Future research should focus on further elucidating Icariin's anti-tumor effects,its application in cartilage tissue engineering and orthopedic biomaterials,and developing novel drug delivery systems to enhance its bioavailability.This research contributed essential knowledge to the study of Icariin.These results may be used in new study areas and to direct drug development.

关 键 词：ICARIIN Herba Epimedii VOSviewer BIBLIOMETRICS 

分 类 号：O62[理学—有机化学]