血管新生与缺血性卒中患者侧支循环建立的研究进展  

Advances in the Study of Angiogenesis and Ischaemic Stroke

作　　者：杨超[1] 姜立刚 YANG Chao;JIANG Ligang(Affiliated Hospital of Beihua University,Jilin City,Jilin Province 132011;Affiliated Hospital of Jilin Medical University,Jilin City,Jilin Province 132013,China)

机构地区：[1]北华大学附属医院,吉林吉林132011 [2]吉林医药学院附属医院,吉林吉林132013

出　　处：《吉林医药学院学报》2024年第5期371-374,共4页Journal of Jilin Medical University

基　　金：吉林省中医药科技项目(2023066);吉林省中医药管理局中风与神经退行性疾病中西医症治重点研究室项目(2022-Z-70);吉林市科技创新发展医疗卫生指导性项目(20230406105)。

摘　　要：缺血性卒中是严重危害人类健康的常见疾病之一,具有高发病率、死亡率及致残率。侧支循环的建立可以增加缺血区脑组织血容量及促进神经功能恢复。近年研究发现,血管新生在缺血性卒中的发生发展中具有重要意义。本文主要从血管新生对缺血区脑组织侧支循环建立的调节机制进行综述,旨在为缺血性卒中的治疗及预后提供帮助。Ischemic stroke is one of the common diseases seriously endangering human health,with a high incidence rate,mortality and disability rate.The establishment of collateral circulation can increase the blood volume of ischemic brain tissue and promote the recov⁃ery of neurological function.In recent years,research has found that angiogenesis plays an important role in the occurrence and develop⁃ment of ischemic stroke.This article mainly reviews the regulatory mechanism of angiogenesis on the establishment of collateral circula⁃tion in ischemic brain tissue,aiming to provide assistance for the treatment and prognosis of ischemic stroke.

关 键 词：缺血性卒中 血管新生 侧支循环 

分 类 号：R743.32[医药卫生—神经病学与精神病学]