等离子体医学研究进展  

Progresses in Plasma Medicine Research

作　　者：卢新培[1] 罗婧怡 聂兰兰 刘大伟 张冠军[2] 刘定新[2] 邵涛[3] 方志 金珊珊 赵亚军 张远涛[5] 邹亮[5] 王晓龙[5] 李和平[6] 张宇[7] 刘东平 杨德正 陈支通 黄青 程诚[10] 吴淑群[11] 刘巧珏 裴学凯 闫旭[13] 程鹤 熊青 石琦 宋珂[16] 曹颖光[16] 陈宏翔 冯爱平[17] 夏育民 白帆[18] 杨春俊[19] 杨润功[20] 何光源[21] LU Xinpei;LUO Jingyi;NIE Lanlan;LIU Dawei;ZHANG Guanjun;LIU Dingxin;SHAO Tao;FANG Zhi;JIN Shanshan;ZHAO Yajun;ZHANG Yuantao;ZOU Liang;WANG Xiaolong;LI Heping;ZHANG Yu;LIU Dongping;YANG Dezheng;CHEN Zhitong;HUANG Qing;CHENG Cheng;WU Shuqun;LIU Qiaojue;PEI Xuekai;YAN Xu;CHENG He;XIONG Qing;SHI Qi;SONG Ke;CAO Yingguang;CHEN Hongxiang;FENG Aiping;XIA Yumin;BAI Fan;YANG Chunjun;YANG Rungong;HE Guangyuan(School of Electrical and Electronic Engineering,Huazhong University of Science and Technology,Wuhan 430074,China;School of Electrical Engineering,Xi'an Jiaotong University,Xi'an 710049,China;Institute of Electrical Engineering,Chinese Academy of Sciences,Beijing 100190,China;School of Electrical Engineering and Control Science,Nanjing University of Technology,Nanjing 211816,China;School of Electrical Engineering,Shandong University,Jinan 250061,China;Department of Engineering Physics,Tsinghua University,Beijing 100084,China;Department of Basic Medical Sciences,Tsinghua University,Beijing 100084,China;School of Electrical Engineering,Dalian University of Technology,Dalian 116024,China;Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences,Shenzhen 518000,China;Institute of Plasma Physics Chinese Academy of Sciences,Hefei 230000,China;College of Automation Engineering,Nanjing University of Aeronautics and Astronautics,Nanjing 210016,China;School of Electrical Engineering and Automation,Wuhan University,Wuhan 430072,China;Beijing Neurosurgical Institute,Beijing 100070,China;School of Chemistry,Nanjing University of Science and Technology,Nanjing 210000,China;School of Electrical Engineering,Chongqing University,Chongqing 400044,China;Tongji Hospital,Tongji Medical College of HUST,Wuhan 430014,China;Union Hospital,Tongji Medical College Huazhong University of Science and Technology,Wuhan 430030,China;The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710000,China;The Second Affiliated Hospital of Anhui Medical University,Hefei 230000,China;The First Medical Center of PLA General Hospital,Beij

机构地区：[1]华中科技大学电气与电子工程学院,武汉430074 [2]西安交通大学电气工程学院,西安710049 [3]中国科学院电工研究所,北京100190 [4]南京工业大学电气工程与控制科学学院,南京211816 [5]山东大学电气工程学院,济南250061 [6]清华大学工程物理系,北京100084 [7]清华大学基础医学院,北京100084 [8]大连理工大学电气工程学院,大连116024 [9]中国科学院深圳先进技术研究院,深圳518000 [10]中国科学院等离子体物理研究所,合肥230000 [11]南京航空航天大学自动化学院,南京210016 [12]武汉大学电气与自动化学院,武汉430072 [13]北京市神经外科研究所,北京100070 [14]南京理工大学化学学院,南京210000 [15]重庆大学电气自动化学院,重庆400044 [16]华中科技大学同济医学院附属同济医院,武汉430014 [17]华中科技大学同济医学院附属协和医院,武汉430030 [18]西安交通大学第二附属医院,西安710000 [19]安徽医科大学第二附属医院,合肥230000 [20]解放军总医院第一医学中心,北京100000 [21]华中科技大学生命科学与技术学院,武汉430074

出　　处：《高电压技术》2024年第8期3555-3579,共25页High Voltage Engineering

基　　金：国家自然科学基金(52130701,52277150);国家重点研发计划(2021YFE0114700)。

摘　　要：大气压非平衡等离子体(atmospheric pressure nonequilibrium plasma,APNP)能够在产生多种活性成分的同时保持较低甚至常温的气体温度,这使得它在生物医学方面有着巨大的应用前景,因此等离子体医学成为一个备受关注的新兴研究领域。自1996年第一篇等离子体医学研究论文发表以来,等离子体医学领域取得了蓬勃的发展,但也面临着一些核心科学问题亟需解决。文中对等离子体医学的研究进展进行了综述,探讨了该领域面临的核心科学问题和等离子体的生物安全性。此外,还简要介绍了等离子体医学在微生物消杀、伤口愈合、癌症治疗、经皮给药和皮肤病治疗等重要应用方面取得的成果。对于制定等离子体医学的标准和规范、建立第三方检测平台以及共享数据库和标准装置等问题,也进行了初步的讨论。最后,对等离子体医学的未来进行了展望。Atmospheric pressure non-equilibrium plasma (APNP) can produce a variety of reactive components while maintaining a low or even ambient gas temperature. Thus APNP possesses tremendous potentials in biomedical applica- tions, and plasma medicine becomes a highly regarded emerging research field. Since the first plasma medicine research paper was published in 1996, the field has seen significant development, although it still faces several core scientific chal- lenges that need to be addressed. This paper reviews the research progress in plasma medicine, and discusses the core scientific issues and the biological safety of plasma. Additionally, this paper briefly introduces the achievements in key applications of plasma medicine, such as microbial sterilization, wound healing, cancer treatment, transdermal drug deliv- ery, and skin disease treatment. Moreover, the formulation of standards and regulations for plasma medicine is preliminarily discussed. Finally, the prospects in the future of plasma medicine are put forward.

关 键 词：等离子体医学 大气压非平衡等离子体 低温等离子体 等离子体源 等离子体诊断 生物医学应用 

分 类 号：O539[理学—等离子体物理]