天津市大气中二氧化氮短期暴露对心血管疾病急救人次的影响  

Impact of short-term exposure to atmospheric nitrogen dioxide on cardiovascular emergency visits in Tianjin,China

作　　者：王玉雯[1] 张经纬[1] 冯利红[1] 崔玉山[1] WANG Yu-wen;ZHANG Jing-wei;FENG Li-hong;CUI Yu-shan(Tianjin Center for Disease Control and Prevention,Tianjin 300011,China)

机构地区：[1]天津市疾病预防控制中心,天津300011

出　　处：《环境卫生学杂志》2024年第8期641-646,共6页JOURNAL OF ENVIRONMENTAL HYGIENE

基　　金：天津市第二批卫生健康行业高层次人才选拔培养工程项目(TJSQNYXXR-D2-151)。

摘　　要：目的探讨天津市大气中二氧化氮(NO_(2))短期暴露对心血管疾病急救人次的影响。方法收集2015-2022年天津市环境空气质量数据、气象数据和急救中心接诊数据。采用基于Poisson回归的广义线性模型,分析大气NO_(2)暴露与心血管疾病急救人次的关系。结果2015-2022年天津市心血管疾病急救人次共计107179人。NO_(2)日均浓度每上升10μg/m^(3),心血管疾病急性发病风险增加1.11%(95%CI:0.42%~1.82%),且存在累积滞后效应。性别分层结果显示,NO_(2)对女性心血管疾病急救人次有影响且存在累积滞后效应,对男性的影响无统计学意义。年龄分层结果显示,NO_(2)对年龄<65岁和年龄≥65岁人群的心血管疾病急救人次均有影响且存在累积滞后效应,对年龄≥65岁人群的影响更为明显。结论大气中NO_(2)污染浓度的升高可能导致心血管疾病急性发病风险的增加,并且具有累积滞后效应。对女性和老年人的影响更为明显。Objective To explore the impact of short-term exposure to atmospheric nitrogen dioxide(NO_(2))on cardiovascular emergency visits in Tianjin,China.Methods Data of Tianjin from 2015 to 2022 were collected,including air quality,meteorological conditions,and emergency visits.A generalized linear model based on Poisson regression was used for the analysis of the relationship between atmospheric NO_(2) exposure and cardiovascular emergency visits.Results A total of 107179 cardiovascular emergency visits were recorded between 2015 and 2022.Each 10μg/m^(3) increase in the daily average concentration of NO_(2) was associated with a 1.11%increase in cardiovascular emergency visits(95%confidence interval:0.42%-1.82%),and there was a cumulative lag effect.Stratified analysis by sex showed that atmospheric NO_(2) had a significant impact on cardiovascular emergency visits among females,also demonstrating a cumulative lag effect,but had an insignificant impact on males.Stratified analysis by age showed that atmospheric NO_(2) influenced cardiovascular emergency visits in both populations under 65 years of age and those aged 65 or older,and there was a cumulative lag effect.The impact was more pronounced in the population aged 65 or older.Conclusion The increase in atmospheric NO_(2) is associated with the increase in cardiovascular emergency visits,and there is a cumulative lag effect,especially for the female and the elderly.

关 键 词：二氧化氮 心血管疾病 急救 时间序列分析 

分 类 号：R122[医药卫生—环境卫生学]