甘油三酯葡萄糖乘积指数和食物摄入量与2型糖尿病综合达标率相关性  

Correlation between triglyceride glucose product index and food intake and type 2 diabetes

作　　者：周君珺 孔维敏 陈进 谢萍[3] 孙雯敏 刘艳梅 郝兰香 王跃琴 倪惠琴 Zhou Junjun;Kong Weimin;Chen Jin;Xie Ping;Sun Wenmin;Liu Yanmei;Hao Lanxiang;Wang Yueqin;Ni Huiqin(School of Nursing,Yangzhou University,Yangzhou 225009;Department of Endocrinology,The First People's Hospital of Yancheng,Yancheng 224000,China;Northern Jiangsu People's Hospital of Jiangsu Province,Yangzhou 225001,China)

机构地区：[1]扬州大学护理学院,扬州225009 [2]盐城市第一人民医院,盐城224000 [3]江苏省苏北人民医院,扬州225001

出　　处：《卫生研究》2024年第5期755-762,共8页Journal of Hygiene Research

基　　金：国家自然科学基金青年项目(No.82300671);江苏省老年健康科研项目(No.LKM2023046);江苏省卫健委科研项目(No.Z2020051)。

摘　　要：目的 探讨甘油三酯葡萄糖乘积指数(triglyceride-glucose index,TyG)和食物摄入量与2型糖尿病患者综合达标率关系的相关性。方法 对盐城市两家医院2020年08月—2023年11月进入国家标准化代谢性疾病管理中心管理的6683名18~75岁的2型糖尿病患者,进行2型糖尿病综合达标率与相关指标关系的分析。采用χ^(2)检验进行单因素分析,借助逐步Logistic回归模型进行多因素分析;并采用限制性立方样条(restricted cubic spline,RCS)分析TyG指数与2型糖尿病综合达标率的线性关联。结果 2型糖尿病患者糖化血红蛋白达标率为9.01%、血压达标率为29.21%、低密度脂蛋白胆固醇达标率为28.51%,综合达标率为1.14%。TyG指数是2型糖尿病综合达标率的阻碍因素。综合达标率与新鲜水果摄入(χ^(2)=32.95,P<0.001)及食盐摄入(χ^(2)=41.92,P<0.001)密切相关,水果摄入量200~400 g有助于提高2型糖尿病患者的综合达标率。结论 TyG指数及水果摄入量、食盐摄入量为综合达标率的相关因素。OBJECTIVE To explore the relationship between triglyceride-glucose index(triglyceride-glucose index) and food intake and the comprehensive compliance rate in patients with type 2 diabetes mellitus(T2DM).METHODS A total of 6683 T2DM patients aged 18 to 75 years entered the National Metabolic Management Center(MMC) in two Yancheng hospitals from August 2020 to November 2023 were selected to analyze the relationship between T2DM standard attainment rate and relevant indicators.Univariate analysis was conducted with χ~2 test,multivariate analysis was conducted with stepwise logistic regression model,and the relationship of TyG to the overall compliance rate of T2DM was analyzed with restricted cubic spline(Restricted Cubic Spline,RCS).RESULTS T2DM patients with glycated hemoglobin Hemoglobin A1c(HbA1c) reached 9.01%,blood pressure(BP) reached 29.21%,low density lipoprotein cholesterol(LDL-C) reached 28.51%,and the comprehensive standard rate was 1.14%.TyG index was the hindering factor affecting the comprehensive standard rate of T2DM.The higher the TyG value,the lower the standard rate.Comprehensive compliance rate and fresh fruit intake(χ~2=32.946,P<0.001) and salt intake(χ~2=41.917,P<0.001) was closely related,and the fruit intake of 200-400 g helped to improve the comprehensive compliance rate of T2DM patients.CONCLUSION TyG index,fruit intake and salt intake may be the influencing factors of comprehensive compliance rate.

关 键 词：2型糖尿病 综合达标 甘油三酯葡萄糖乘积指数 水果 

分 类 号：R151[医药卫生—营养与食品卫生学] R153[医药卫生—公共卫生与预防医学]