磁性壳聚糖复合微球对血红素吸附性能的研究  

Adsorption performance of magnetic chitosan composite microspheres on hemoglobin

作　　者：金星鹏 詹炜君 陈俪锟 陈丽 JIN Xingpeng;ZHAN Weijun;CHEN Likun;CHEN Li(School of Pharmacy,Jiangsu Ocean University,Lianyungang 222005;Jiangsu Provincial Institute of Marine Resources Development,Jiangsu Ocean University,Lianyungang 222005)

机构地区：[1]江苏海洋大学药学院,连云港222005 [2]江苏海洋大学江苏省海洋资源开发研究院,连云港222005

出　　处：《中国食品添加剂》2024年第9期179-187,共9页China Food Additives

摘　　要：以壳聚糖为基体,将Fe_(3)O_(4)包覆其中,形成磁性壳聚糖微球(MCS)。采用机械化学合成法合成了氢氧化镧-磁性壳聚糖微球复合材料(MCL)。考察MCS/La(OH)_(3)不同质量比和不同因素对血红素吸附量的影响。采用多种表征手段对MCL2形貌结构、热稳定和磁性能进行研究。通过BET和XPS图谱,结合吸附动力学对MCL2的吸附机理进行详尽分析。结果表明,MCL2即MCS/La(OH)_(3)质量比为1∶0.8时具有较好的吸附性能和磁性能。当血红素浓度为90 mg/L,45℃下反应1 h时可得到最佳吸附量19.7562 mg/g。MCL2为核壳结构,表面粗糙,热稳定性好,磁分离能力强。MCL2以化学和物理作用对血红素进行吸附,吸附过程符合准二级动力学模型。MCL2凭借优秀的吸附性能,有望成为一种有效富集纯化血红素的材料。Magnetic chitosan microspheres(MCS)were prepared by encapsulating Fe_(3)O_(4) within chitosan matrix.La(OH)3-magnetic chitosan microsphere composite(MCL)were synthesized via mechanochemical synthesis.The effects of different MCS/La(OH)_(3) mass ratios and other factors on hemoglobin adsorption capacity were investigated.MCL2 was characterized by various methods to analyze its morphology,structure,thermal stability,and magnetic properties.The adsorption mechanism of MCL2 were explored using BET and XPS analyses,combined with adsorption kinetics.The results showed that MCL2 exhibited optimal adsorption and magnetic properties at an MCS to La(OH)_(3) mass ratio of 1∶0.8.The maximum adsorption capacity of 19.7562 mg/g was achieved at a hemoglobin concentration of 90 mg/L,and reaction temperature of 45℃for 1 hour.MCL2 possesses a core-shell structure with a rough surface,good thermal stability,and strong magnetic separation capabilities.Hemoglobin adsorption onto MCL2 occurred through both chemical and physical interactions,following a quasi-second-order kinetic model.The excellent adsorption performance of MCL2 indicates its potential as a promising material for the effective enrichment and purification of hemoglobin.

关 键 词：磁性 壳聚糖 氢氧化镧 血红素 吸附 

分 类 号：TS202.3[轻工技术与工程—食品科学]