经导管卵圆孔未闭封堵术联合氟桂利嗪治疗PFO伴偏头痛患者的效果  

Effect of Transcatheter Patent Foramen Ovale Occlusion Combined with Flunarizine in the Treatment of Patients with PFO and Migraine

作　　者：葛立永 GE Liyong(The People's Hospital of Qiannan Buyi and Miao Autonomous Prefecture,Duyun 558000,China)

机构地区：[1]黔南布依族苗族自治州人民医院,贵州都匀558000

出　　处：《中外医学研究》2024年第25期142-145,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:分析经导管卵圆孔未闭(PFO)封堵术联合氟桂利嗪治疗PFO伴偏头痛患者的效果。方法:选取2021年5月—2023年5月黔南布依族苗族自治州人民医院收治的84例PFO伴偏头痛患者作为研究对象,按随机数表法将患者分为对照组与观察组,各42例。对照组行经导管PFO封堵术治疗,观察组在对照组基础上给予氟桂利嗪治疗。比较两组临床疗效、头痛发作情况、头痛程度及生活质量。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。治疗前,两组头痛发作情况、头痛影响测评量表-6(HIT-6)及健康调查量表(SF-36)各维度评分相比,差异无统计学意义(P>0.05);治疗后,两组头痛发作情况优于治疗前,HIT-6评分低于治疗前,SF-36各维度评分高于治疗前,且观察组优于对照组,差异有统计学意义(P<0.05)。结论:经导管PFO封堵术联合氟桂利嗪能减轻PFO伴偏头痛患者头痛程度,减少头痛发作频率,提升生活质量。Objective:To analyze the effect of transcatheter patent foramen ovale(PFO)occlusion combined with Flunarizine in the treatment of patients with PFO and migraine.Method:A total of 84 patients with PFO and migraine who admitted to the People's Hospital of Qiannan Buyi and Miao Autonomous Prefecture from May 2021 to May 2023 were selected as the study objects,the patients were divided into the control group and the observation group according to the random number table method,with 42 cases in each group.The control group was treated with transcatheter PFO closure,and the observation group was treated with Flunarizine on the basis of the control group.The clinical efficacy,headache attack,headache degree and quality of life were compared between two groups.Result:The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).Before treatment,there were no significant differences in the headache attack,headache impact assessment scale-6(HIT-6)score and health survey scale(SF-36)score between two groups(P>0.05);after treatment,the headache attack of two groups were better than those before treatment,the HIT-6 scores were lower than those before treatment,the scores of SF-36 each dimension were higher than those before treatment,and those in the observation group were better than those in the control group,the differences were statistically significant(P<0.05).Conclusion:Transcatheter PFO occlusion combined with Flunarizine can reduce the degree of headache in patients with PFO and migraine,reduce the frequency of headache attacks and improve the quality of life.

关 键 词：卵圆孔未闭 偏头痛 经导管卵圆孔未闭封堵术 氟桂利嗪 生活质量 

分 类 号：R747.2[医药卫生—神经病学与精神病学] R541.1[医药卫生—临床医学]