Ligation-assisted endoscopic submucosal resection following unroofing technique for small esophageal subepithelial lesions originating from the muscularis propria  

作　　者：Quan Lu Quan-Zhou Peng Jun Yao Li-Sheng Wang De-Feng Li 

机构地区：[1]Department of Gastroenterology,Shenzhen People’s Hospital,Shenzhen 518020,Guangdong Province,China [2]Department of Pathology,Shenzhen People’s Hospital,Shenzhen 518020,Guangdong Province,China [3]Department of Gastroenterology,Shenzhen People’s Hospital,The Second Clinical Medical College,Jinan University,Shenzhen 518020,Guangdong Province,China [4]The First Affiliated Hospital,Southern University of Science and Technology,Shenzhen 518020,Guangdong Province,China

出　　处：《World Journal of Gastroenterology》2024年第32期3748-3754,共7页世界胃肠病学杂志（英文版）

基　　金：Supported by the Engineering Training Funds in Shenzhen,No.SYLY201718,No.SYJY201714,and No.SYLY201801;Technical Research and Development Project of Shenzhen,No.JCYC20170307100911479,No.JCYJ20190807145617113,No.JCYJ20210324113802006.

摘　　要：BACKGROUND The majority of esophageal subepithelial lesions originating from the muscularis propria(SEL-MPs)are benign in nature,although a subset may exhibit malignant characteristics.Conventional endoscopic resection techniques are time-consuming and lack efficacy for small SEL-MPs.AIM To evaluate the efficacy and safety of ligation-assisted endoscopic submucosal resection(ESMR-L)following unroofing technique for small esophageal SEL-MPs.METHODS From January 2021 to September 2023,17 patients diagnosed with esophageal SEL-MPs underwent ESMR-L following unroofing technique at the endoscopy center of Shenzhen People’s Hospital.Details of clinicopathological characteristics and clinical outcomes were collected and analyzed.RESULTS The mean age of the patients was 50.12±12.65 years.The mean size of the tumors was 7.47±2.83 mm and all cases achieved en bloc resection successfully.The average operation time was 12.2 minutes without any complications.Histopathology identified 2 Lesions(11.8%)as gastrointestinal stromal tumors at very low risk,12 Lesions(70.6%)as leiomyoma and 3 Lesions(17.6%)as smooth muscle proliferation.No recurrence was found during the mean follow-up duration of 14.18±9.62 months.CONCLUSION ESMR-L following roofing technique is an effective and safe technique for management of esophageal SEL-MPs smaller than 20 mm,but it cannot ensure en bloc resection and may require further treatment.

关 键 词：Subepithelial lesions Muscularis propria ESOPHAGUS LIGATION Endoscopic submucosal resection 

分 类 号：R571[医药卫生—消化系统]