Clinical characteristics of patients with early gastric prematurity cancer and analysis of complications by endoscopic resection  

作　　者：Hong Zhao Xiang-Yu Shi Li-Li Lv Yan-Zong Lai Xiao-Xiao Bao Jian-Wen Hu 

机构地区：[1]Department of Gastroenterology,Dongyang People’s Hospital,Dongyang 322100,Zhejiang Province,China [2]Department of Gastroenterology,Yiwu Tianxiang Medical East Hospital,Yiwu 322100,Zhejiang Province,China [3]Department of Pathology,Dongyang People’s Hospital,Dongyang 322100,Zhejiang Province,China

出　　处：《World Journal of Gastrointestinal Oncology》2024年第9期3898-3904,共7页世界胃肠肿瘤学杂志（英文版）（电子版）

摘　　要：BACKGROUND Gastric cancer,a prevalent malignancy,poses a severe threat to the health of residents in China.Timely intervention in early stages can extend patients’survival.AIM To analyze clinical characteristics of patients with early gastric cancer and efficacy and risk of complications associated with endoscopic resection.METHODS This study included 175 patients with early gastric cancer treated at our hospital,with no restrictions on sex or age.General data,pathological information,and endoscopic biopsy results were obtained.The clinical characteristics of early gastric cancer were analyzed,and endoscopic resection was performed.Postoperative efficacy and incidence of complications were monitored.Statistical analysis was performed using SPSS 26.0 and GraphPad Prism 8.0 software.RESULTS A total of 175 patients with early gastric cancer were included,with 75.43%(n=132)males and 24.57%(n=43)females.38.29%(n=67)and 35.43%(n=62)of patients had a history of smoking and alcohol consumption,respectively.Comorbidities included diabetes(8.57%,n=15),coronary heart disease(10.29%,n=18),and hypertension(43.43%,n=76),which was highly prevalent.A history of abdominal surgery and family history of digestive system cancer accounted for 21.14%and 17.14%,respectively.The most common lesion location was the antral part of the stomach(52.00%,n=91),followed by the gastric angle,body,and fundus.The pathological types were predominantly high-grade intraepithelial neoplasia(28.00%,n=49)and well-differentiated adenocarcinoma(26.86%,n=47),followed by moderately differentiated adenocarcinoma,high-moderately differentiated adenocarcinoma,and moderate-lowly differentiated adenocarcinoma.89.14%of the patients had intestinal metaplasia and 85.14%had atrophy.After endoscopic resection,re-examination revealed that 13 patients had cancer cells at the tissue margin,with a positive margin rate of 7.43%.Postoperative complications included no cases of gastrointestinal obstruction,but incisional infection(2.86%,n=5),gastric perforation(1.14%,n=2)

关 键 词：Early gastric cancer Clinical characteristics Endoscopic resection COMPLICATIONS 

分 类 号：R735.2[医药卫生—肿瘤]