How to"pick up"colorectal serrated lesions and polyps in daily histopathology practice:From terminologies to diagnostic pitfalls  

作　　者：Thai H Tran Vinh H Nguyen Diem TN Vo 

机构地区：[1]Department of Pathology,Da Nang Hospital,Da Nang 50000,Viet Nam [2]Department of Pathology,University Medical Center Ho Chi Minh City,Ho Chi Minh 70000,Viet Nam [3]Department of Histology-Embryology and Pathology,University of Medicine and Pharmacy at Ho Chi Minh City,Ho Chi Minh 70000,Viet Nam

出　　处：《World Journal of Clinical Oncology》2024年第9期1157-1167,共11页世界临床肿瘤学杂志（英文版）

摘　　要：Over the last decade,our knowledge of colorectal serrated polyps and lesions has significantly improved due to numerous studies on this group of precursor lesions.Serrated lesions were misleading as benign before 2010,but they are currently reclassified as precancerous lesions that contribute to 30%of colorectal cancer through the serrated neoplasia pathway.The World Health Organization updated the classification for serrated lesions and polyps of the colon and rectum in 2019,which is more concise and applicable in daily practice.The responsible authors prescribe that“colorectal serrated lesions and polyps are characterized by a serrated(sawtooth or stellate)architecture of the epithelium.”From a clinical standpoint,sessile serrated lesion(SSL)and SSL with dysplasia(SSLD)are the two most significant entities.Despite these advancements,the precise diagnosis of SSL and SSLD based mainly on histopathology remains challenging due to various difficulties.This review describes the nomenclature and the terminology of colorectal serrated polyps and lesions and highlights the diagnostic criteria and obstacles encountered in the histopathological diagnosis of SSL and SSLD.

关 键 词：Sessile serrated lesions Sessile serrated lesions with dysplasia Serrated polyps Sessile serrated adenoma Benign hyperplastic polyps Serrated lesions/polyps 

分 类 号：R735.34[医药卫生—肿瘤]