New therapy for metabolic syndrome:Gut microbiome supplementation  

作　　者：Waseem Qureshi Maqsood Ahmad Dar Mohd Younis Rather 

机构地区：[1]Hospital Administration,Government Medical College,University of Kashmir,Jammu and Kashmir,Srinagar 190010,India [2]Department of Medicine,Government Medical College,University of Kashmir,Jammu and Kashmir,Srinagar 190010,India [3]Multidisciplinary Research Unit,Government Medical College,University of Kashmir,Jammu and Kashmir,Srinagar 190010,India

出　　处：《World Journal of Diabetes》2024年第9期1833-1836,共4页世界糖尿病杂志（英文版）（电子版）

摘　　要：The gut microbiota is important in the development and progression of metabolic illnesses such type 2 diabetes,cardiovascular disease(CVD),and obesity.This diverse community of microorganisms controls a variety of physiological functions,including metabolism,inflammation,and immune response.Understanding these interactions has resulted in novel therapeutic options,including microbiome supplementation.The gut microbiome is extremely susceptible to dietary changes,which can alter its makeup and function,influencing metabolite synthesis that affects host health.Certain metabolites,such as butyrate and propionate,have been proven to protect against metabolic illnesses,whereas trimethylamine has been linked to CVD.Prebiotics,probiotics,synbiotics,and postbiotics are being investigated by researchers as ways to change the gut microbiome and boost metabolic health.Despite advances in therapy and lifestyle adjustments,the prevalence of metabolic syndrome is increasing,emphasizing the need for new medicines.

关 键 词：PROBIOTICS PREBIOTICS SYNBIOTICS Postbiotics MICROBIOME Type 2 diabetes mellitus Cardiovascular disease Obesity 

分 类 号：R587.1[医药卫生—内分泌]