Prediction model establishment and validation for enteral nutrition aspiration during hospitalization in patients with acute pancreatitis  

作　　者：Ping Hou Hao-Jun Wu Tang Li Jia-Bin Liu Quan-Qing Zhao Hong-Jiang Zhao Zi-Ming Liu 

机构地区：[1]Division II of General Surgery,West China Hospital-Chengdu Shangjin Nanfu,West China Hospital,Sichuan University,Chengdu 611730,Sichuan Province,China [2]Division of Biliary Tract Surgery,West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China [3]Department of Hepatobiliary and Pancreatic Surgery,West China Hospital-Chengdu Shangjin Nanfu,West China Hospital,Sichuan University,Chengdu 611730,Sichuan Province,China [4]Department of Thyroid Surgery,West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China [5]Department of Oncology,West China Hospital-Chengdu Shangjin Nanfu,West China Hospital,Sichuan University,Chengdu 611730,Sichuan Province,China [6]Division of Biliary Tract Surgery,Department of General Surgery,West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China

出　　处：《World Journal of Gastrointestinal Surgery》2024年第8期2583-2591,共9页世界胃肠外科杂志（英文版）（电子版）

摘　　要：BACKGROUND Acute pancreatitis(AP)is a disease caused by abnormal activation of pancreatic enzymes and can lead to self-digestion of pancreatic tissues and dysfunction of other organs.Enteral nutrition plays a vital role in the treatment of AP because it can meet the nutritional needs of patients,promote the recovery of intestinal function,and maintain the barrier and immune functions of the intestine.However,the risk of aspiration during enteral nutrition is high;once aspiration occurs,it may cause serious complications,such as aspiration pneumonia,and suffocation,posing a threat to the patient’s life.This study aims to establish and validate a prediction model for enteral nutrition aspiration during hospitalization in patients with AP.AIM To establish and validate a predictive model for enteral nutrition aspiration during hospitalization in patients with AP.METHODS A retrospective review was conducted on 200 patients with AP admitted to Chengdu Shangjin Nanfu Hospital,West China Hospital of Sichuan University from January 2020 to February 2024.Clinical data were collected from the electronic medical record system.Patients were randomly divided into a validation group(n=40)and a modeling group(n=160)in a 1:4 ratio,matched with 200 patients from the same time period.The modeling group was further categorized into an aspiration group(n=25)and a non-aspiration group(n=175)based on the occurrence of enteral nutrition aspiration during hospitalization.Univariate and multivariate logistic regression analyses were performed to identify factors influencing enteral nutrition aspiration in patients with AP during hospitalization.A prediction model for enteral nutrition aspiration during hospitalization was constructed,and calibration curves were used for validation.Receiver operating characteristic curve analysis was conducted to evaluate the predictive value of the model.RESULTS There was no statistically significant difference in general data between the validation and modeling groups(P>0.05).The comparison of age,gend

关 键 词：Acute pancreatitis HOSPITALIZATION Enteral nutrition Predictive model ASPIRATION 

分 类 号：R576[医药卫生—消化系统]