Global research landscape of Peutz-Jeghers syndrome and successful endoscopic management of intestinal intussusception in patients with recurrent laparotomies  

作　　者：Qi Sun Xiao-Ying Wang Guang-Jin Guo Lei Wang Li-Min Meng Yun-Fei Guo Tao Sun Shou-Bin Ning 

机构地区：[1]Department of Gastroenterology,Air Force Medical Center,Beijing 100142,China [2]College of Life Science,Northwest University,Xi'an 710069,Shaanxi Province,China [3]Clinical Medical Laboratory,Air Force Medical Center,Beijing 100142,China [4]Department of Medical Imaging,Air Force Medical Center,Beijing 100142,China [5]Department of Pathology,Air Force Medical Center,Beijing 100142,China

出　　处：《World Journal of Gastrointestinal Surgery》2024年第8期2702-2718,共17页世界胃肠外科杂志（英文版）（电子版）

基　　金：Capital Health Development Research Special Project,No.2020-4-5123.

摘　　要：BACKGROUND Peutz-Jeghers syndrome(PJS)has brought significant physical,psychological and economic burdens on the patients and their families due to its early onset,diagnostic and therapeutic challenges and increased recurrence risk.AIM To explore the current research status and emerging hotspots of PJS.METHODS Studies on PJS published during 1994-2023 were gathered based on Web of Science Core Collection.Additionally,a case of PJS-induced intestinal intussusception,successfully treated with endoscopic methods despite three laparotomies,was highlighted.Comprehensive bibliometric and visual analysis were conducted with VOSviewer,R and CiteSpace.RESULTS Altogether 1760 studies were identified,indicating a steady increase in the publication number.The United States had the highest influence,whereas the University of Helsinki emerged as the leading institution,and Aaltonen LA from the University of Helsinki was the most prolific author.Cancer Research,Oncogene and Endoscopy were the top three journals based on H-index.Keyword burst direction analysis revealed that"cancer risk","management","surveillance"and"familial pancreatic cancer"were the potential hotspots for investigation.Additionally,"early detection","capsule endoscopy","clinical management","double-balloon endoscopy","familial pancreatic cancer"and"molecular genetic basis"were identified as the key clusters of co-cited references.Endoscopic polypectomy remained effective on resolving intestinal intussusception in patients who underwent three previous laparotomies.CONCLUSION In the last three decades,global publications related to PJS show a steadily increasing trend in number.Endoscopic management is currently a research hotspot.

关 键 词：Peutz-Jeghers syndrome ENDOSCOPY Management Cancer MICROBIOTA BIBLIOMETRIC 

分 类 号：R574.3[医药卫生—消化系统]