Viral etiologies of acute liver failure  

作　　者：Brian W McSteen Xiao-Han Ying Catherine Lucero Arun B Jesudian 

机构地区：[1]Department of Medicine,New York-Presbyterian/Weill Cornell Campus,New York,NY 10021,United States [2]Department of Gastroenterology and Hepatology,Weill Cornell Medicine,New York,NY 10021,United States

出　　处：《World Journal of Virology》2024年第3期26-40,共15页世界病毒学杂志

摘　　要：Acute liver failure(ALF)is a rare cause of liver-related mortality worldwide,with an estimated annual global incidence of more than one million cases.While drug-induced liver injury,including acetaminophen toxicity,is the leading cause of ALF in the Western world,viral infections remain a significant cause of ALF and the most common cause in many developing nations.Given the high mortality rates associated with ALF,healthcare providers should be aware of the broad range of viral infections that have been implicated to enable early diagnosis,rapid treatment initiation when possible,and optimal management,which may include liver transplantation.This review aims to provide a summary of viral causes of ALF,diagnostic approaches,treatment options,and expected outcomes.

关 键 词：Acute liver failure Viral hepatitis Hepatitis B Hepatitis C Hepatitis A Liver disease HEPATOLOGY 

分 类 号：R575[医药卫生—消化系统]