Supervised vs home-based exercise program in kidney transplant recipients: A pilot pragmatic non-randomized study  

作　　者：Anna Crepaldi Giovanni Piva Nicola Lamberti Michele Felisatti Luca Pomidori Yuri Battaglia Fabio Manfredini Alda Storari Pablo Jesús López-Soto 

机构地区：[1]Unit of Nephrology,University Hospital of Ferrara,Ferrara 44121,Emilia-Romagna,Italy [2]Department of Nursing,Instituto Maimónides de Investigación Biomédica de Córdoba,Cordoba 14004,Andalusia,Spain [3]Department of Neuroscience and Rehabilitation,University of Ferrara,Ferrara 44121,Emilia-Romagna,Italy [4]Esercizio Vita Medical Fitness,Ferrara 44124,Emilia-Romagna,Italy [5]Department of Medicine,University of Verona,Verona 37100,Veneto,Italy [6]Department of Nursing,Maimonides Biomedical Research Institute of Cordoba,University of Cordoba,Reina Sofía University Hospital,Cordoba 14004,Andalusia,Spain

出　　处：《World Journal of Transplantation》2024年第4期123-132,共10页世界移植杂志

摘　　要：BACKGROUND Although the benefits of exercise for kidney transplant recipients(KTRs)have been widely demonstrated,these patients experience several barriers in undertaking a structured exercise program in hospital and non-hospital facilities.AIM To compare the effects of a supervised moderate-intensity gym-based intervention with a home-based low-intensity walking program on exercise capacity in KTRs.METHODS KTRs were asked to choose between two six-month programs.The first group performed a low-intensity interval walking intervention at home-based exercise intervention (HBex). The second group performed a supervised training program at an adapted physical activitygym (Sgym), including aerobic and resistance training. The outcomes, collected at baseline and at the end of theprograms, included the 6-minute walking test, the peak oxygen consumption (VO_(2)peak) during a treadmill test,the 5-time sit-to-stand test, and blood pressure.RESULTSSeventeen patients agreed to participate and self-selected into the HBex (n = 9) and Sgym (n = 8) groups. Twopatients in the Sgym group dropped out because of familial problems. At baseline, patients in the HBex group weresignificantly older and had lower walking distance, VO_(2)peak, and lower limb strength. Primary outcome changeswere significantly greater in the HBex group than in the Sgym group (52 ± 23 m vs 8 ± 34;P = 0.005). No othersignificant differences between groups were observed. Both groups improved most of the outcomes in the withingroupcomparisons, with significant variations in VO_(2) peak.CONCLUSIONSix-month moderate-intensity supervised or low-intensity home-based training programs effectively improvedexercise capacity in KTRs. Gym-based programs combine aerobic and resistance training;however, in-homewalking may be proposed for frail KTRs.

关 键 词：EXERCISE TRANSPLANTATION WALKING Training NEPHROLOGY Kidney disease 

分 类 号：R699.2[医药卫生—泌尿科学]