免疫分析仪精密移液控制技术设计  

Design of precise pipetting control technology for immunoassay analyzer

作　　者：杜家杰 金振华 赵凤 韩爱民 王京华 王芳芳 Du Jiajie;Jin Zhenhua;Zhao Feng;Han Aimin;Wang Jinghua;Wang Fangfang(Shandong Zhonghong Special Inspection Biotechnology Co.,Ltd.,Jinan 250000,China;Shandong Academy of Pharmaceutical Sciences,Jinan 250101,China)

机构地区：[1]山东中鸿特检生物科技有限公司,济南250000 [2]山东省药学科学院,济南250101

出　　处：《现代仪器与医疗》2024年第4期46-50,共5页Modern Instruments & Medical Treatment

基　　金：山东省科技型中小企业创新能力提升工程(2023TSGC0228)。

摘　　要：目的为实现免疫分析仪精密自动检测,精密自动移液技术至关重要。本课题主要研究免疫分析仪精密移液控制技术,作为免疫分析仪重要部件,其控制精度与自动化程度直接决定最终检测结果的准确性及检测效率,是系统的关键组成部分。方法本系统通过PID闭环负反馈自动控制技术来实现免疫分析仪精密移液控制,通过单片机伺服电机驱动控制技术、高精度传感器检测及低通滤波技术等方法设计免疫分析仪精密移液控制技术。结果本文系统性的给出了免疫分析仪精密移液控制系统软硬件及控制算法设计,设计并解决免疫分析仪精确移液控制技术设计问题,提高加样系统电机控制精度及加样精度,使得加样精度达到加样量10μL时±5%或200μL时±3%。结论本系统可以很好的解决当前免疫分析仪精密移液控制设计技术问题,从而提高免疫分析仪控制精度、移液加样精度及检测效率。Objective In order to achieve precise automatic detection of immune analyzers,precise automatic pipetting technology is crucial.This project mainly studies the precision pipetting control technology of the immune analyzer.As an important component of the immune analyzer,its control accuracy and automation level directly determine the accuracy and efficiency of the final detection results,and it is a key component of the system.Methods The system had realized the precision pipetting control of the immune analyzer by PID closed-loop negative feedback automatic control technology,and designed the precision pipetting control technology of the immune analyzer by single-chip servo motor drive control technology,high-precision sensor detection and low-pass filtering technology.Results In this paper,the hardware and software of precision pipetting control system of immune analyzer and the control algorithm were systematically designed and solved.The design of precise pipetting control technology of immune analyzer was designed and solved.The precision of motor control and sampling accuracy of the sampling system was improved,and the sampling accuracy reached±5%at 10μL or±3%at 200μL.Conclusion This system can solve the technical problems of precision pipetting control design of immunoanalyzer,and improve the control precision,pipetting sampling precision and detection efficiency of immunoanalyzer.

关 键 词：AVR单片机 电机驱动技术 PID控制算法 低通滤波1 

分 类 号：TH776[机械工程—仪器科学与技术] TP18[机械工程—精密仪器及机械]