逆向肿瘤心脏病学的研究进展  

Research progress in reverse cardio-oncology

作　　者：胡鑫 么宇彤 贺玉泉[1] Hu Xin;Yao Yutong;He Yuquan(Department of Cardiology,China-Japan Union Hospital of Jilin University,Changchun 130033,China)

机构地区：[1]吉林大学中日联谊医院心血管内科,长春130033

出　　处：《中华心力衰竭和心肌病杂志（中英文）》2024年第2期151-156,共6页Chinese Journal of Heart Failure and Cardiomyopathy

基　　金：吉林省自然科学基金(YDZJ202301ZYTS516)。

摘　　要：心血管疾病(CVD)和癌症是两种不同的疾病,然而最新研究发现,CVD患者患癌症的风险增加,由此出现一个新的概念——逆向肿瘤心脏病学,虽然逆向肿瘤心脏病学领域的研究逐渐成为热点,且已有研究证实,心脏重构、药物性高血压及心力衰竭都能够促进肿瘤进程,但CVD促进癌症的具体机制尚不清楚。据此,我们对CVD促进癌症进程的证据,逆向肿瘤心脏病学的研究进展及未来发展方向进行综述,以期为逆向肿瘤心脏病学领域的研究提供新思路。Although cardiovascular disease(CVD)and cancer are two different diseases,recent studies have found an increased risk of developing cancer among patients with CVD.This has led to the emergence of a new concept,reverse cardio-oncology.Research in this field is becoming increasingly popular,and studies have confirmed that cardiac remodeling,pharmacological hypertension,and heart failure can promote tumor progression.However,the specific mechanisms by which CVD promotes cancer are still unknown.Therefore,we review the evidence for the promotion of cancer by CVD,the progress of research in reverse cardio-oncology,and future directions,in order to provide new ideas for research in this field.

关 键 词：逆向肿瘤心脏病学 心脏分泌因子 癌症发病率 

分 类 号：R730.5[医药卫生—肿瘤] R54[医药卫生—临床医学]