老年精神分裂症患者复发影响因素及与营养状况的相关性分析  

Analysis of factors influencing relapse in elderly patients with schizophrenia and its correlation with nutritional status

作　　者：王威 任华[1] 代光智[1] 汪子琪 WANG Wei;REN Hua;DAI Guangzhi(Logistics Support Department of Chengdu Fourth People's Hospital,Chengdu 610036,China)

机构地区：[1]成都市第四人民医院,成都610036

出　　处：《国际精神病学杂志》2024年第4期1057-1060,共4页Journal Of International Psychiatry

基　　金：成都市科技项目(编号:2022-YF05-01883-SN)。

摘　　要：目的分析老年期精神分裂症患者复发的影响因素及其与营养状况的相关性。方法选择2022年1月~2022年12月我院老年期精神分裂症患者130例,均开展1年随访,依据简明精神病评定量表(Brief Psychiatric Rating Scale,BPRS)结果将其分为复发组(n=43),未复发组(n=87)。比较两组基线资料,及入院时营养风险筛查2002评分(Nutrition Risk Screening2002,NRS2002),微型营养评定法(mini-nutritional assessment,MNA)评分。采用多因素Logistic回归分析老年期精神分裂症复发的影响因素。结果复发组身体质量指数(body mass index,BMI)<25kg/m2,病程≥5年,家族史阳性,服药不依从,NRS2002≥3分,MNA<24分的占比均高于未复发组(P<0.05);经多因素Logistic回归分析证实,BMI<25kg/m2,病程≥5年,家族史阳性,服药不依从,NRS2002≥3分,MNA<24分均为老年期精神分裂症复发的危险因素,均P<0.05。结论患者BMI,病程,家族史,服药依从性及营养状况均为患者复发的影响因素,营养不良将增加患者复发风险,应对营养失衡患者给予重点关注,及时采取干预措施,减少复发可能性。Objective The influence factors of relapse in elderly patients with schizophrenia and its correlation with nutritional status.Methods 130 elderly patients with schizophrenia in our hospital from January 2022 to December 2022 were selected and followed up for 1 year.According to the results of the Brief Psychiatric Rating Scale(BPRS),they were divided into a recurrent group(n=43)and a non recurrent group(n=87)Nutritional Risk Screening2002(NRS2002)and mini-nutritional assessment(MNA)scores were compared between the two groups.Multivariate Logistic regression was used to analyze the influencing factors of relapse in elderly schizophrenia.Results The proportion of body mass index(BMI)<25kg/m2,disease course≥5 years,positive family history,drug noncompliance,NRS2002≥3 points,MNA<24 points in relapse group was higher than that in non-relapse group(P<0.05).Multivariate Logistic regression analysis confirmed that BMI<25kg/m2,duration≥5 years,positive family history,non-compliance,NRS2002≥3 points,MNA<24 points were all risk factors for relapse of elderly schizophrenia,all with P<0.05.Conclusion The BMI,duration,family history,medication adherence and nutrition are the influence factors of patients with recurrence,patients with malnutrition will increase the risk of recurrence,should focus on the patients with nutritional imbalance,take timely intervention measures to reduce the possibility of recurrence.

关 键 词：老年期精神分裂症 营养状况 复发 微型营养评定法 营养风险筛查2002评分 

分 类 号：R749.3[医药卫生—神经病学与精神病学]