毛舌的病因和发病机制研究进展  

Research Progress in Etiology and Pathogenesis of Hairy Tongue

作　　者：吴思华 陈谦明 WU Sihua;CHEN Qianming(State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases&National Key Laboratory of Oral Mucosal Diseases&Innovation Unit of Oral Mucosal Carcinogenesis and Prevention,Chinese Academy of Medical Sciences&Department.of Oral Medicine,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China)

机构地区：[1]口腔疾病研究国家重点实验室、国家口腔疾病临床医学研究中心、口腔黏膜病国家临床重点专科、中国医学科学院口腔黏膜癌变与防治创新单元、四川大学华西口腔医院黏膜病科,四川成都610041

出　　处：《口腔医学研究》2024年第9期757-761,共5页Journal of Oral Science Research

基　　金：国家自然科学基金(编号:81991502)。

摘　　要：毛舌是一种发生在舌背的毛发状病损,可被食物、烟草或者显色的微生物染色,从而呈现多种颜色如白色、黄褐色和黑色。毛舌是一种良性损害,但可引起口腔异味、口干、美观等问题,使患者生活质量降低。目前毛舌的发病机制尚未阐明,本文总结现有研究下毛舌的病因和发病机制,其可能涉及丝状乳头代谢异常、口腔微生物失衡、免疫异常状态和相关药物的使用。Hairy tongue is a hairy lesion on the dorsal surface of the tongue that can be stained by food,tobacco,or microorganisms,resulting in a variety of colors such as white,tan,and black.Hairy tongue is a kind of benign lesions that can cause halitosis,dry mouth,aesthetic problems,so that patients’quality of life is reduced.At present,the pathogenesis of hairy tongue has not been clarified.This review summarizes current studies on the etiology and pathogenesis of hairy tongue,which may be related to metabolic abnormality of filiform papillae,oral microbiota imbalance,immune abnormal phenomenon,and use of certain drugs.

关 键 词：毛舌 黑毛舌 病因 发病机制 

分 类 号：R781[医药卫生—口腔医学]