主动防控风险干预应用在重症肝硬化伴上消化道出血患者药物治疗期间的效果  

Effect of Active Prevention and Control Risk Intervention During Drug Treatment in Patients with Severe Cirrhosis and Upper Gastrointestinal Bleeding

作　　者：袁晓敏 尉晓琳 谢东文[1] YUAN Xiaomin;WEI Xiaolin;XIE Dongwen(Intensive Care Unit,Anyang Fifth People’s Hospital,Anyang 455000,Henan,China)

机构地区：[1]安阳市第五人民医院重症监护室,河南安阳455000

出　　处：《中国药物滥用防治杂志》2024年第8期1445-1449,共5页Chinese Journal of Drug Abuse Prevention and Treatment

基　　金：河南省科技发展计划项目(编号:232102311236)。

摘　　要：目的:评估主动防控风险干预措施在重症肝硬化伴上消化道出血患者药物治疗中的临床效果。方法:回顾性选取2021年3月—2023年10月我院接受治疗的重症肝硬化伴上消化道出血患者72例,依据患者入院的先后顺序分为对照组和观察组,每组36例。对照组给予常规流程进行干预,观察组采用主动防控风险干预模式,比较两组临床相关指标、负性情绪、睡眠质量、舒适度、生活质量、并发症发生率及干预满意度。结果:干预后,观察组止血时间、住院时间短于对照组,再出血次数及出血量少于对照组(P<0.05);观察组SAS、SDS评分低于对照组(P<0.05);观察组PSQI评分低于对照组,GCQ及SF-36评分高于对照组(P<0.05);观察组并发症总发生率低于对照组,干预满意度高于对照组(P<0.05)。结论:主动防控风险干预应用于药物治疗重症肝硬化合并上消化道出血患者中效果显著,有利于改善其出血症状、降低再出血发生风险,改善负性情绪,提升干预满意度。Objective:To evaluate the clinical effect of active prevention and control risk intervention measures in the drug treatment of patients with severe cirrhosis and upper gastrointestinal bleeding.Methods:From March 2021 to October 2023,72 patients with severe cirrhosis and upper gastrointestinal bleeding treated in our hospital were retrospectively selected.According to the order of admission,the patients were divided into control group and observation group,with 36 patients in each group.The control group was given routine process intervention,and the observation group was given active prevention and control risk intervention mode.The clinical related indicators,negative emotions,sleep quality,comfort,quality of life,complication rate and intervention satisfaction were compared between the two groups.Results:After intervention,the hemostasis time and hospitalization time of the observation group were shorter than those of the control group,and the number of rebleeding and the amount of bleeding were less than those of the control group(P<0.05).The scores of SAS and SDS in the observation group were lower than those in the control group(P<0.05).The PSQI score of the observation group was lower than that of the control group,and the GCQ and SF-36 scores were higher than those of the control group(P<0.05).The total incidence of complications in the observation group was lower than that in the control group,and the intervention satisfaction was higher than that in the control group(P<0.05).Conclusion:Active prevention and control risk intervention has a significant effect on patients with severe cirrhosis and upper gastrointestinal bleeding treated with drugs,which is beneficial to improve their bleeding symptoms,reduce the risk of rebleeding,improve negative emotions,and improve intervention satisfaction.

关 键 词：重症肝硬化 上消化道出血 主动防控风险干预 干预效果 

分 类 号：R575.2[医药卫生—消化系统] R969.4[医药卫生—内科学]